Biosynthesis, characterization and therapeutic applications of plant-mediated silver nanoparticles (original) (raw)
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PLANT MEDIATED SYNTHESIS OF SILVER NANOPARTICLES AND THEIR BIOLOGICAL ACTIVITY
Biological methods of synthesis have paved way for " greener synthesis " of nanoparticles and these have proven to be better methods due to slower kinetics, they offer better manipulation and control over crystal growth and their stabilization. This has motivated an upsurge in research on the synthesis routes that allow better control of shape and size for various nanotechnological applications. In this work, we have explored an inventive contribution for synthesis of silver nanoparticles using catharanthus roseus (Sadabahar), Musa paradisiacal (Plantain flower) and Polygonum odoratum (Coriandium) leaf extract. Synthesized nanoparticles were characterized by various methods such as UV-Vis spectroscopy, SEM and XRD. In addition, antibacterial activity of the synthesized silver nanoparticles was also determined. This new method is rapid time scales for biosynthesis of metallic nanoparticles using environmentally benign natural resources as an alternative to chemical synthesis protocols as reductant for synthesizing silver nanoparticles. 250 | P a g e
Synthesis and Antimicrobial Activity of Plant Based Silver Nanoparticles - A Review
Bioscience Biotechnology Research Communications, 2020
Nanotechnology is an exciting and influential world of manufacturing nanoparticles that find varied medicines, bacterial studies, wastewater treatment, and many more applications. This review paper aims to review the synthesis of silver nanoparticles from horticultural sources and evaluate special applications causing a considerable impact on the environment. Conventionally silver nanoparticles are produced by various chemical and physical processes. Biosynthesis of silver nanoparticles offers alternative methods, where plant extract can be used instead of harmful chemicals. Among various nanoparticles, silver nanoparticles possess unique antibacterial and antiviral properties make them superior to other nanoparticles. The green chemistry approach for synthesizing silver nanomaterials is environmentally friendly, benign, and gaining wide popularity. Enzymes, proteins, phytochemicals, phytochelatin, and vitamins are biomolecules found in plant extracts. In the process of biosynthesis of AgNPs, plant extracts act as good reducing, capping agents.. Biomolecules help reduce and stabilize the process of silver nanoparticles. The biomolecules enhance the yield process of biosynthesis of AGNP. This review highlights a summary of silver nanoparticle biosynthesis and their antibacterial activity. Silver nanoparticles is a multidisciplinary area that has gained focus from researchers of diverse areas from science, pharmaceuticals, agriculture, and materials engineering due to their morphologies and composition. Various physical and chemical techniques for synthesis include biological methods, chemical reduction, electron irradiation, gamma irradiation, laser ablation, microwave processing, and photochemical methods. The authors have attempted to compile the reported studies regarding silver nanoparticle synthesis from plants and their specific antibacterial properties. This paper reviews various synthesis techniques from plant materials and medical applications of silver nanoparticles. An attempt is made to present the current state and future silver nanoparticle applications in general and antibacterial treatments in particular.
Plant mediated synthesis of silver nanoparticles-tapping the unexploited sources
scholarsresearchlibrary.com
Interest in "green nanotechnology" in nanoparticle biosynthesis is growing among researchers. Nanotechnologies, due to their physicochemical and biological properties, have applications in diverse fields, including drug delivery, sensors, optoelectronics, and magnetic devices. This review focuses on the green synthesis of silver nanoparticles (AgNPs) using plant sources. Green synthesis of nanoparticles is an eco-friendly approach, which should be further explored for the potential of different plants to synthesize nanoparticles. The sizes of AgNPs are in the range of 1 to 100 nm. Characterization of synthesized nanoparticles is accomplished through UV spectroscopy, X-ray diffraction, Fourier transform infrared spectroscopy, transmission electron microscopy, and scanning electron microscopy. AgNPs have great potential to act as antimicrobial agents. The green synthesis of AgNPs can be efficiently applied for future engineering and medical concerns. Different types of cancers can be treated and/or controlled by phytonanotechnology. The present review provides a comprehensive survey of plant-mediated synthesis of AgNPs with specific focus on their applications, e.g., antimicrobial, antioxidant, and anticancer activities.
Synthesis of silver nanoparticles from plant extracts and their antimicrobial application
International Journal of Biosciences (IJB)
Development of reliable and eco-friendly process for synthesis of nanoparticles is an important step in the field the of nanotechnology. Nanotechnology involves the tailoring of materials at the atomic level to attain unique properties, which can be suitably manipulated for the desired applications. Among them silver nanoparticles draw attention due to its unique physical, chemical and biological properties. Green principle route of synthesizing have emerged as alternative to overcome the limitation of conventional methods among which plant and microorganisms are majorly exploited. Employing plants towards synthesis of nanoparticles are emerging as advantageous compared to microbes with the presence of broad variability of bio molecules in plants can act as capping and reducing agents and thus increases the rate of reduction and stabilization of nanoparticles. This review focuses on the green synthesis of silver nanoparticles using various plant sources and its applications in cancer treatment. Generally surgery, chemotherapy and radiation treatment are the most prevalent therapeutic option for cancer. Unfortunately these treatments have various side effects due to lack of targeted delivery and cancer specificity. To overcome these limitations, nanoparticle could ensure targeted drug therapy having very little side effects. In this review focus is given to silver nanoparticle, synthesized from natural plant extracts, as it is cost effective, eco-friendly, stable and safe in cancer treatment.
Engineering a reliable and eco-accommodating methodology for the synthesis of metal nanoparticles is a crucial step in the field of nanotechnology. Plant-mediated synthesis of metal nanoparticles has been developed as a substitute to defeat the limitations of conventional synthesis approaches such as physical and chemical methods. Biomolecules, such as proteins, amino acids, enzymes, flavonoids, and terpenoids from several plant extracts have been used as a stabilising and reducing agents for the synthesis of AgNPs. Regardless of an extensive range of biomolecules assistance in the synthesis procedure, researchers are facing a significant challenge to synthesise stable and geometrically controlled AgNPs. In the past decade, several efforts were made to develop Plant-mediated synthesis methods to produce stable, cost effective and eco-friendly AgNPs. More than hundred different plants extract sources for synthesising AgNPs were described in the last decade by several researchers. Most of the reviews were focused on various plant sources for synthesis, various characterization techniques for characteristic analysis, and antibacterial activity against bacterial. There are many reviews are available for the plant-mediated synthesis of AgNPs as well as antibacterial activity of AgNPs but this is the first review article mainly focused on biomolecules of plants and its various parts and operating conditions involved in the synthesis. Apart from, this review includes the characterisation of AgNPs and antibacterial activity of such nanoparticles with size, shape and method used for this study.
Plant-Based Synthesis of Silver Nanoparticles and Their Characterization
Nanotechnology and Plant Sciences, 2015
Nanotechnology is a very promising area of research which involves the production of nanomaterials as the basic strategy. Although artificial synthesis of nanomaterials were initiated by using chemical and physical approaches, but recently the biological synthesis methods are being widely used as ecofriendly alternatives. Plant-based synthesis of nanomaterials is better because of its ease of handling, rapidity, and cost-effective nature along with environmental friendliness. A wide range of applications of silver nanoparticles (AgNPs) creates a focal point for attention of researchers. In view of published studies, in this chapter, we critically assess the role of plants in the synthesis of AgNPs, the characterization methods, applications of biologically synthesized AgNPs in various fields and future perspectives.
Plant Science Today, 2017
Now days, the development of safe, cost effective, reliable and eco-friendly processes for the synthesis of nanoparticles is an important aspect of nanotechnology. Among the various agents, plants show immense potential for the synthesis of nanoparticles. The bio-molecules found in plants induce reduction of Ag+ ions from silver nitrate to silver nanoparticles (AgNPs); therefore, in the present work, the aqueous leaves extract of the plant was used as reducing agent for the synthesis of silver nanoparticles. We synthesized extracellular silver nanoparticles using extract of the leaves of four different medicinal plants which act as a reducing agent at room temperature. The characteristic color change was observed on addition of plant extract to the silver nitrate solution due to their specific properties (Surface Plasmon Resonance). UV-Vis spectroscopy was used for the characterization of the silver nanoparticles. Green synthesized nanoparticles are evaluated for their antimicrobial...
Plant-mediated Biosynthesis of Silver Nanoparticles and Evaluation of Their Antibacterial Activities
Aqueous seed extract of Syzygium cumini (SCE) was used for the synthesis of silver (Ag) nanoparticles. The nanoparticles were characterized with the help of UV–vis spectrophotometer, Particle size analyser (PSA), Transmission electron microscopy (TEM) and Fourier transform infrared spectroscopy (FTIR). UV-Vis spectra of silver nanoparticles shows absorbance peak at 440 nm. The nanoparticles synthesized were relatively spherical in shape with varying sizes. The biosynthesized silver nanoparticles were found to be highly toxic against some human pathogenic bacteria.
J. Chem. Bio. Phy. Sci. Sec. B, 2019
Nanotechnology introduced the concept of nanoparticles, which exhibit unique and remarkably different properties from their bulk materials. Chemical methods are widely used among various strategies of synthesizing nanoparticles. Green synthesis is utilized as a cost effective and environmentally friendly alternative to the chemical method of synthesizing nanoparticles. Plant mediated synthesis of the nanoparticles is recognized as most promising green synthesis method and researchers have paid closer attention to the green synthesis of silver nanoparticles due to their remarkable antimicrobial activity. The review focus on the recent studies and present the methodology used in bio-reduction of silver nitrate solution using plant extracts, methods used in characterization of synthesized nanoparticles, various antibacterial assays conducted and also giving a brief overview of the results obtained from them
Biosynthesis of silver nanoparticles using plant extracts: an update
2019
In the recent period, different types of nanoparticles (NPs) have been proposed to improve antioxidant, but also antimicrobial properties of various natural compounds. Much attention has been dedicated to synthesis of NPs using biogenic enzymatic processes. The biosynthesis of NPs has been claimed to be superior to chemical synthesis, especially because of the opportunity of producing more environment-friendly and less toxic products. Among the numerous types of NPs, bioreduction-produced silver NPs from ionic silver-containing solutions are receiving much attention. In this work, we present an update on our investigation on biosynthesis of silver NPs (AgNPs), thus presenting a method of reduction of silver nitrate solution, using a plant decoct from black pepper fruit (Piper nigrum, L). Namely, we present biosynthesis of AgNPs from 1 mmol/L AgNO3 solution, by bioreduction that was provided from the complex composition of pepper fruit extract, obtained by decoction. The formation of...