Regulation of the transcription factor Ets-1 by DNA-mediated homo-dimerization (original) (raw)

Structural Insights into the Autoregulation and Cooperativity of the Human Transcription Factor Ets-2

Christopher Cooper

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Recent advances in the structural molecular biology of Ets transcription factors: interactions, interfaces and inhibition

Christopher Cooper

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Solution structure of the ETS domain from murine Ets-1: A winged helix-turn-helix DNA binding motif

Logan Donaldson

The EMBO Journal

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Structures of the Ets Protein DNA-binding Domains of Transcription Factors Etv1, Etv4, Etv5, and Fev

Christopher Cooper

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Steric Mechanism of Auto-Inhibitory Regulation of Specific and Non-Specific DNA Binding by the ETS Transcriptional Repressor ETV6

Soumya De, Anson Chan

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A single amino-acid substitution in the Ets domain alters core DNA binding specificity of Ets1 to that of the related transcription factors Elf1 and E74

Jacques Ghysdael

Nucleic Acids Research, 1993

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Structural transition of ETS1 from an auto-inhibited to functional state upon association with the p16 INK4a native and mutated promoter region

Dr. Kannan M

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Structural coupling of the inhibitory regions flanking the ETS domain of murine Ets-1

Logan Donaldson

Protein Science, 2008

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Conserved structural features of ETS domain-DNA complexes

Andrei Alexeevski

Molecular Biology, 2009

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The Affinity of Ets1 for DNA is Modulated by Phosphorylation Through Transient Interactions of an Unstructured Region

Miles Pufall

Journal of Molecular Biology, 2008

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Conformational Dynamics and the Binding of Specific and Nonspecific DNA by the Autoinhibited Transcription Factor Ets-1

Geneviève Desjardins

Biochemistry, 2016

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Secondary Structure of the ETS Domain Places Murine Ets-1 in the Superfamily of Winged Helix-Turn-Helix DNA-Binding Proteins

Logan Donaldson

Biochemistry, 1994

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Cooperative binding of Ets-1 and core binding factor to DNA

Jacques Ghysdael

Molecular and cellular biology, 1994

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Regulation of TCF ETS-domain transcription factors by helix-loop-helix motifs

Paula Yates

Nucleic Acids Research, 2003

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An inhibitory carboxyl-terminal domain in Ets-1 and Ets-2 mediates differential binding of ETS family factors to promoter sequences of the mb-1 gene

James Hagman

Proceedings of the National Academy of Sciences, 1992

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Genome-Wide Analyses Reveal Properties of Redundant and Specific Promoter Occupancy Within the ETS Gene Family

CHRISTOPHER HOPKINS

Genes & …, 2007

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New Insights on DNA Recognition by ets Proteins from the Crystal Structure of the PU.1 ETS Domain-DNA Complex

Francesca Pio

Journal of Biological Chemistry, 1996

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Heterogeneous dynamics in DNA site discrimination by the structurally homologous DNA-binding domains of ETS-family transcription factors

James Bashkin

Nucleic acids research, 2015

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The Structural and Dynamic Basis of Ets1 DNA Binding Autoinhibition

Miles Pufall

Journal of Biological Chemistry, 2005

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Proteins of the ETS family with transcriptional repressor activity

Jacques Ghysdael

Oncogene, 2000

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Correction of the NMR structure of the ETS1/DNA complex

Joseph Shiloach

Journal of biomolecular NMR, 1997

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DNA binding by c-Ets-1, but not v-Ets, is repressed by an intramolecular mechanism

N. Kraut

The EMBO Journal, 1992

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Structural Analysis of the Autoinhibition of Ets1 and Its Role in Protein Partnerships

Miles Pufall

Journal of Biological Chemistry, 2002

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Variable Control of Ets1 DNA Binding by Multiple Phosphates in an Unstructured Region

Miles Pufall

Science, 2005

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DNA Occupancy of Polymerizing Transcription Factors: A Chemical Model of the ETS Family Factor Yan

matthew hope

Biophysical Journal, 2017

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Autoinhibition of ETV6 (TEL) DNA Binding: Appended Helices Sterically Block the ETS Domain

Soumya De

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The PEA3 Ets Transcription Factor Comprises Multiple Domains That Regulate Transactivation and DNA Binding

John Hassell

Journal of Biological Chemistry, 2001

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Auto-Inhibition and Partner Proteins, Core-Binding Factor beta (CBFbeta ) and Ets-1, Modulate DNA Binding by CBFalpha 2 (AML1)

Ting-Lei Gu

Molecular and Cellular Biology, 2000

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Molecular Dynamics and Structural Studies of the Ets Domain-DNA Complexes

Rafael Caceres

Current Bioinformatics, 2007

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p300/cAMP-responsive Element-binding Protein Interactions with Ets-1 and Ets-2 in the Transcriptional Activation of the Human Stromelysin Promoter

Catherine Duggan

Journal of Biological Chemistry, 1999

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Co-crystallization of an ETS Domain (PU.1) in Complex with DNA

Richard Mitchell

Journal of Biological Chemistry, 1995

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The functional subunit of a dimeric transcription activator protein depends on promoter architecture

Richard Ebright

Trends in Genetics, 1995

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