The role of adipose tissue as an endocrine gland (original) (raw)

Adipose tissue, previously viewed merely as a lipid storage depot, plays a significant role as an active endocrine organ, secreting adipocytokines that influence whole-body metabolism and are linked to conditions such as insulin resistance and cardiovascular disease. Key adipokines like adiponectin and resistin have been implicated in metabolic dysfunction, with differences in their expression and function between visceral and subcutaneous fat emphasizing the need to redefine obesity based on fat distribution rather than just volume.