Coexistence Of Squamous Cell CarcinomaWith Dermoid Cyst Of Ovary:A Case Report (original) (raw)
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Squamous Cell Carcinoma Arising in a Dermoid Cyst Ovary: A Rare Case Report
2016
Dermoid cysts account for approximately 25% of all ovarian tumors. Presence of pure squamous cell carcinoma is very rare findings (1-2%), which is attributable to malignant transformations into a pre-existing dermoid cyst. As there are no specific signs and symptoms to suggest malignancy in dermoid cyst, therefore it is difficult to predict, and most cases are diagnosed post-operatively. We hereby report a case of dermoid cyst ovary with malignant transformation into squamous cell carcinoma in 50 years post-menopausal women. Who presented with complaint of abdominal pain and increased frequency of micturation. Hysterectomy with Bilateral-salpingo-oophorectomy (BSO) with omentectomy was done. Right ovary showed huge cyst with hair shaft, sebaceous materials and a small solid area. Histopathological examination revealed squamous cell carcinoma was arising within the dermoid cyst.
Squamous cell carcinoma arising in a dermoid cyst of the ovary: A case series
Bangladesh Medical Research Council Bulletin
Background: Malignant transformation in a dermoid cyst of the ovary is a rare complication, occurring in only 1-2% of cases, with squamous cell carcinoma being the most common type. Preoperative diagnosis is difficult because of the lack of specific symptoms and signs to suggest malignancy. The prognosis is generally poor when disease has spread beyond the ovary. Objective: This study was conducted to review experience with this disease and describe the current treatment modality. Methods: It was identified 4 women with this diagnosis during 2013-2018. This is a descriptive study, looking at the patient’s characteristics, mode of presentation, the role of tumor markers and radiological imaging in diagnosis. It was also examined the stage and pathological features of the presentation and subsequent course of the disease. Result: The median age was 45 (range: 32-63 yrs). Three cases were stage I and one case was stage III. The average tumor diameter was 14.1cm. All patients were und...
Primary Squamous Cell Carcinoma of Ovary- a Case Report with Review of Literature
Journal of Evidence Based Medicine and Healthcare
BACKGROUND Ovarian squamous cell carcinoma is a very rare malignancy and its occurrence is generally seen associated with transformation of an existing ovarian dermoid cyst. The de novo occurrence of squamous cell carcinoma of the ovary in the absence of an antecedent ovarian dermoid is extremely rare. We report a case of 35-year-old female patient evaluated for abdominal distension. Abdominal CT was suggestive of a malignant neoplastic mass. Laparotomy was performed, which confirmed a malignant tumour involving the right adnexa and extending into the bowel and surrounding omentum. Surgical debulking, total hysterectomy with bilateral salpingo-oophorectomy, omentectomy and bowel resection was performed. Histopathological examination demonstrated squamous cell carcinoma arising from right ovary with no existing dermoid.
Journal of Gynecologic Surgery, 2017
Background: Squamous-cell carcinoma (SCC) of the ovary arising from an epidermoid cyst is an exceptionally rare occurrence. SCC presenting with a metastatic nodule in the myometrium has not yet been reported in literature. Most commonly, SCC arises from mature cystic teratomas of the ovaries. It presents with nonspecific signs and symptoms in postmenopausal females. Case: This article reports on a case of pure SCC of the ovary with metastasis to the myometrium in a 55-year-old postmenopausal female that was diagnosed on a histopathologic examination. Results: Histopathologic examination led to the diagnosis of well-differentiated SCC originating from the epidermoid cyst of the ovary and metastasizing to the uterus. Conclusions: Preoperative radiologic diagnosis is challenging; hence, postoperative histopathologic examination is essential for a final diagnosis. Serum markers, such as SCC antigen and CA-125, help in making a provisional diagnosis of SCC. Due to the rarity of such cases in the literature, treatment options are not clearly understood. (J GYNECOL SURG XX:1
Collision tumor: serous cystadenocarcinoma and dermoid cyst in the same ovary
Archives of Gynecology and Obstetrics, 2009
Introduction Collision tumor means the coexistence of two adjacent, but histologically distinct tumors without histologic admixture in the same tissue or organ. Collision tumors involving ovaries are extremely rare. Case We present a case of 45-year-old parous woman with a left dermoid cyst, with unusual imaging Wndings, massive ascites and peritoneal carcinomatosis. The patient underwent cytoreductive surgery. The histopathology revealed a collision tumor consisting of an invasive serous cystadenocarcinoma and a dermoid cyst.
Malignant transformation of ovarian dermoid: a rare case
International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2013
Mature cystic teratoma also known as the dermoid cyst is the most common benign tumor of the ovary (10-20%) in women of reproductive age. Malignant transformation in a dermoid is very rare (<2%) with squamous cell carcinoma being the most common malignancy. A total of 36 ovarian cysts have been operated in our hospital from the year February 2007 to April 2012 of which about 90% were dermoid but no case of ovarian dermoid turned malignant have been reported till date in our state, Sikkim, India. We report a rare case of dermoid cyst of ovary in a 47 yr old woman which had malignant transformation. Surgeons should keep the chance of malignant transformation in mind when faced with a dermoid cyst especially in older patients or in larger than usual so that the best can be done for the patient regarding the staging of the disease and its further management.
Gynecologic Oncology Reports, 2017
Mature cystic teratomas (MCT), also known as dermoid cysts, are the most common ovarian germ cell tumors and the most common ovarian neoplasms in patients younger than 20 years. Malignant transformation (MT) is a rare complication of MCTs which may occur in 1-2% of the cases. Squamous cell carcinoma (SCC) is the most frequent histology arising from MCTs and its appearance depends on diverse risk factors such as patient's age, the size of the tumor and levels of serum tumor markers. Diagnosis and treatment constitute a big challenge due to the rarity and the aggressive course of this entity. Adjuvant chemotherapy has a leading role in the treatment of MCT-arising SCC, while the use of radiotherapy or chemoradiation is still under consideration. Herein, we report a case of a post-menopausal woman, presenting with mild symptoms and a large pelvic mass deriving from the left ovary occurring as dermoid cyst. Simultaneously, we review the literature stressing out the prognostic factors and the treatment options for MCT arising SCC according to traditional and new therapy-strategies.
International journal of clinical and experimental pathology, 2010
A rare case of multiple malignant tumors (poorly differentiated squamous cell carcinoma and high grade osteosarcoma) arising in an ovarian dermoid cyst of a 55 year old female is reported. To the best of our knowledge, this is the first well documented example of such an unusual combination of tumors arising in a dermoid cyst. The osteosarcoma and squamous cell carcinoma appear to arise in the background of benign teratomatous environment of a dermoid cyst rather than from "pure" mixed mesodermal tumors of the ovary. The tumors did not appear to have well demarcated boundaries with a junction or close intermingling of both cell types, features less favorable for collision tumor or carcinosarcoma. Despite extensive surgery with negative surgical margins and combination chemotherapy, the patient had recurrence of the tumor within four months and she died secondary to septicemia to chemotherapy and bilateral pulmonary emboli shortly after.