HIV-1 tat protein stimulates transcription by binding to a U-rich bulge in the stem of the TAR RNA structure (original) (raw)

Human Immunodeficiency Virus 1 Tat Protein Binds Trans-Activation-Responsive Region (TAR) RNA in vitro

Mohinder Singh

Proceedings of The National Academy of Sciences, 1989

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In silico analyses of subtype specific HIV-1 Tat-TAR RNA interaction reveals the structural determinants for viral activity

Larance Ronsard

Frontiers, 2017

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Distinct Transcriptional Pathways of TAR-Dependent and TAR-Independent Human Immunodeficiency Virus Type-1 Transactivation by Tat

Gilbert Morris

Virology, 1997

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The TAR Hairpin of Human Immunodeficiency Virus Type 1 Can Be Deleted When Not Required for Tat-Mediated Activation of Transcription

Ben Berkhout

Journal of Virology, 2007

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Requirement for HIV-1 TAR sequences for Tat activation in rodent cells

Martin Braddock

Virology, 1995

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Effect of the Position of TAR on Transcriptional Activation by HIV-1 Tatin Vivo

Stephanie Wright

Journal of Molecular Biology, 1996

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The single-stranded DNA binding protein, Pur-α, binds HIV-1 TAR RNA and activates HIV-1 transcription

Edward W. Johnson

Gene, 1998

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Identification of a novel HIV-1 TAR RNA bulge binding protein

Martin Braddock

Nucleic Acids Research, 1994

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TAR-RNA binding by HIV1 Tat protein is selectively inhibited by its L-enantiomer

Francois Hamy

Nucleic Acids Research, 1998

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HIV-1 TAT “activates” presynthesized RNA in the nucleus

Martin Braddock, A. Chambers

Cell, 1989

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HIV-1 Tat amino acid residues that influence Tat-TAR binding affinity: a scoping review

Monray Williams

BMC Infectious Diseases

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The Apical Loop of the HIV-1 TAR RNA Hairpin Is Stabilized by a Cross-loop Base Pair

Tadeusz Kulinski

Journal of Biological Chemistry, 2003

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Impact of Genetic Variations in HIV-1 Tat on LTR-Mediated Transcription via TAR RNA Interaction

Larance Ronsard, Tripti Rai, Nilanjana Ganguli, Akhilfaculty Nii, Suhnrita Chaudhuri

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Mechanism of HIV-1 Tat RNA translation and its activation by the Tat protein

Marcelo López-Lastra

Retrovirology, 2009

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Analysis of Tat transactivation of human immunodeficiency virus transcription in vitro

B. Ensoli

Gene expression, 1992

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Destabilization of the TAR hairpin affects the structure and function of the HIV-1 leader RNA

Ben Berkhout

Nucleic Acids Research, 2008

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The HIV-1 Tat Protein Has a Versatile Role in Activating Viral Transcription

Ben Berkhout

Journal of Virology, 2011

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A Human Immunodeficiency Virus Type 1 (HIV-1) Tat Cofactor Absent in Rodent Cells is a TAR-associated Factor

Peter Shank

Immune Network, 2002

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Impact of Naturally Occurring Genetic Variation in the HIV-1 LTR TAR Region and Sp Binding Sites on Tat-Mediated Transcription

Brian Wigdahl

Journal of Human Virology & Retrovirology, 2015

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Association of HIV1 Tat with the Cellular Protein, Puralpha , Is Mediated by RNA

Sameer Ansari

Proceedings of The National Academy of Sciences, 1999

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Evolution of a disrupted TAR RNA hairpin structure in the HIV-1 virus

Ben Berkhout

The EMBO journal, 1994

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Altering the Context of an RNA Bulge Switches the Binding Specificities of Two Viral Tat Proteins

Shane Crotty

Biochemistry

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An Evolved RNA Recognition Motif That Suppresses HIV-1 Tat/TAR-Dependent Transcription

Ite Laird-offringa

ACS chemical biology, 2016

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New, extended hairpin form of the TAR-2 RNA domain points to the structural polymorphism at the 5' end of the HIV-2 leader RNA

Katarzyna Purzycka

Nucleic Acids Research, 2006

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Site-Specific Cross-Linking of Amino Acids in the Basic Region of Human Immunodeficiency Virus Type 1 Tat Peptide to Chemically Modified TAR RNA Duplexes

Leonid Beigelman

Biochemistry, 1998

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TAR RNA loop: A scaffold for the assembly of a regulatory switch in HIV replication

Yueh-Hsin Ping

Proceedings of the National Academy of Sciences, 2002

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Human immunodeficiency virus type 1 and 2 Tat proteins specifically interact with RNA polymerase II

Sai-Hong Ou

Proceedings of the National Academy of Sciences, 1996

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The HIV1 transcriptional activator Tat has potent nucleic acid chaperoning activities in vitro

Roman Storchak

Nucleic Acids Research, 2008

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Human immunodeficiency virus type 1 Tat-mediated trans activation correlates with the phosphorylation state of a cellular TAR RNA stem-binding factor

Peter Shank

Journal of Virology, 1992

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The Tat Protein of Human Immunodeficiency Virus Type 1 (HIV-1) Can Promote Placement of tRNA Primer onto Viral RNA and Suppress Later DNA Polymerization in HIV-1 Reverse Transcription

Rodney Russell, M. Morgan

Journal of Virology, 2002

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The sequence and structure of the 3' arm of the first stem-loop of the human immunodeficiency virus type 2 trans-activation responsive region mediate Tat-2 transactivation

S. Hedderwick

Journal of virology, 1997

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Sequence-specific interaction of Tat protein and Tat peptides with the transactivation-responsive sequence element of human immunodeficiency virus type 1 in vitro

Vinod Sardana

Proceedings of the National Academy of Sciences, 1990

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Transition Step during Assembly of HIV Tat:P-TEFb Transcription Complexes and Transfer to TAR RNA

I. D'Orso, G. Jang, Alexander Pastuszak

Molecular and Cellular Biology, 2012

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