TLR signaling is activated in lymph-node resident CLL cells and is only partially inhibited by ibrutinib Conflicts of Interest (original) (raw)

TLR signaling is activated in lymph-node resident CLL cells and is only partially inhibited by ibrutinib

Arthur Shaffer

Cancer Research, 2018

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Heterogeneous Functional Effects of Concomitant B Cell Receptor and TLR Stimulation in Chronic Lymphocytic Leukemia with Mutated versus Unmutated Ig Genes

Achilles Anagnostopoulos, Chrysoula Belessi

The Journal of Immunology, 2014

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Sensitization of IL2 Signaling through TLR-7 Enhances B Lymphoma Cell Immunogenicity

Jenny Mena

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Ibrutinib treatment improves T cell number and function in CLL patients

Jennifer Woyach

The Journal of clinical investigation, 2017

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New insights into the regulation of TLR signaling

sinead miggin

Journal of Leukocyte Biology, 2006

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TLR2 Expression on Leukemic B Cells from Patients with Chronic Lymphocytic Leukemia

Agata Szymańska

Archivum immunologiae et therapiae experimentalis, 2018

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Lymphoma Cell Immunogenicity through TLR-7 Enhances B Sensitization of IL2 Signaling

Jenny Mena

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Molecular and cellular mechanisms of CLL: novel therapeutic approaches

Tanja Hartmann

Nature Reviews Clinical Oncology, 2009

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Immunostimulatory Effects of Triggering TLR3 Signaling Pathway — Implication for Cancer Immunotherapy

Mohamed Salem

Immune Response Activation, 2014

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Human Lymphatic Endothelial Cells Express Multiple Functional TLRs

Michael Pepper

The Journal of Immunology, 2008

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TLR agonists: our best frenemy in cancer immunotherapy

Ann Joseph

Journal of Leukocyte Biology, 2013

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Heterodimer-specific TLR2 stimulation results in divergent functional outcomes in B-cell precursor acute lymphoblastic leukemia

Amina Kariminia

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The role of TLR activation in inflammation

Ian Sabroe

The Journal of Pathology, 2008

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NF-κB1 and c-Rel cooperate to promote the survival of TLR4 activated B cells by neutralizing Bim via distinct mechanisms

Andreas Strasser

2008

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Critical molecular pathways in CLL therapy

Emili Montserrat

Molecular medicine (Cambridge, Mass.), 2018

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A phase I/II trial of TLR-7 agonist immunotherapy in chronic lymphocytic leukemia

Reg Gorczynski

Leukemia, 2009

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Regulation of T cell activation by TLR ligands

Dieter Kabelitz

European Journal of Cell Biology, 2011

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Ibrutinib and venetoclax target distinct subpopulations of CLL cells: implication for residual disease eradication

Madina Sukhanova

2021

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Cleaved/Associated TLR3 Represents the Primary Form of the Signaling Receptor

Toufic Renno, M. Bonnin, Jean-jacques Pin

The Journal of Immunology, 2013

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Ibrutinib Does Not Impact CCR7-Mediated Homeostatic Migration in T-Cells from Chronic Lymphocytic Leukemia Patients

Stefanie Wissmann

Cancers

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Immunomodulatory effects of Toll-like receptor-7 activation on chronic lymphocytic leukemia cells

Jenny Mena

Leukemia, 2006

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NF- B1 and c-Rel cooperate to promote the survival of TLR4-activated B cells by neutralizing Bim via distinct mechanisms

Andreas Strasser

Blood, 2008

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