Autism Spectrum Disorder Symptoms and Comorbidity in Emerging Adults (original) (raw)

Psychiatric Comorbidity and Functioning in a Clinically Referred Population of Adults with Autism Spectrum Disorders: A Comparative Study

Journal of Autism and Developmental Disorders, 2013

To systematically examine the patterns of psychiatric comorbidity and functioning in clinically referred adults with autism spectrum disorders (ASD). Psychiatrically referred adults with and without ASD were compared on measures assessing for psychiatric comorbidity and psychosocial functioning. Sixty-three adults with ASD participated in the study (mean age: 29 ± 11 years). Adults with ASD in their lifetime suffered from a higher burden of psychiatric disorders (6 ± 3.4 vs. 3.5 ± 2.7; p \ 0.001) including major depressive disorder and multiple anxiety disorders, and were functionally more impaired with a significant proportion having received both counseling and pharmacotherapy. Adults with ASD have high levels of psychiatric comorbidity and dysfunction comparable to a clinically referred population of adults without ASD.

Russell et al. - 2015 - The mental health of individuals referred for assessment of ASD in adulthood A clinic report.pdf

Growing awareness of autism spectrum disorders has increased the demand for diagnostic services in adulthood. High rates of mental health problems have been reported in young people and adults with autism spectrum disorder. However, sampling and methodological issues mean prevalence estimates and conclusions about specificity in psychiatric comorbidity in autism spectrum disorder remain unclear. A retrospective case review of 859 adults referred for assessment of autism spectrum disorder compares International Classification of Diseases, Tenth Revision diagnoses in those that met criteria for autism spectrum disorder (n = 474) with those that did not (n = 385). Rates of psychiatric diagnosis (>57%) were equivalent across both groups and exceeded general population rates for a number of conditions. The prevalence of anxiety disorders, particularly obsessive compulsive disorder, was significantly higher in adults with autism spectrum disorder than adults without autism spectrum disorder. Limitations of this observational clinic study, which may impact generalisability of the findings, include the lack of standardised structured psychiatric diagnostic assessments by assessors blind to autism spectrum disorder diagnosis and inter-rater reliability. The implications of this study highlight the need for careful consideration of mental health needs in all adults referred for autism spectrum disorder diagnosis.

Autism spectrum disorders in adults with intellectual disability and comorbid psychopathology: Scale development and reliability of the ASD-CA

Research in Autism Spectrum Disorders, 2008

Researchers and clinicians have generally agreed that persons with autism spectrum disorders (ASD) are susceptible to other DSM Axis I disorders. However, to date, little has been done to establish the specific disorders, their rate and severity of occurrence, and their interrelationship with ASD symptoms. One reason for the lack of research has been the absence of a comorbidity measure for this population. Additionally, when research has been conducted, it typically has been on one disorder with young children. The present study assessed comorbid DSM Axis I disorders in adults with ASD, either autism or PDDNOS and intellectual disabilities, using a new scale designed for the purpose. The reliability and factor structure of the scale was evaluated and implications for future research are discussed. #

Age of Autism Spectrum Disorder Diagnosis and Comorbidity in Children and Adolescents with Autism Spectrum Disorder

Developmental Neurorehabilitation

Aim: Research is required to study the relationship between age of autism spectrum disorder (ASD) diagnosis and the presence of comorbidities. Method: The Gastrointestinal Symptom Inventory, Autism Spectrum Disorder-Comorbid for Children, Behavior Problem Inventory-Short Form and Social Communication Questionnaire were completed by parents of 129 children and adolescents with a diagnosis of ASD. Results: Results revealed significant relationships between the age of ASD diagnosis, the presence of comorbidities and intellectual disability. Significant correlations were found between the age of ASD diagnosis and self-injurious and stereotyped behavior. Comorbid psychopathology significantly predicted the presence of GI symptoms. In addition, the relationship between comorbid psychopathology and challenging behavior in this study was reported as bi-directional as both comorbidities predicted one another in the sample. Conclusion: Future research needs to consider the role of comorbidities in relation to ASD diagnosis.

Comorbid psychological disorder in individuals with intellectual disabilities and autism spectrum disorders

2008

Autism spectrum disorders (ASD) are characterized by deficits in three areas of functioning: communication, socialization, and restricted interests/repetitive behavior. With the rise in diagnoses of ASD in recent years, these disorders have received increasing recognition by researchers and clinicians. These efforts have largely been with young children. However, the study of ASD and comorbid disorders in adults with intellectual disability (ID) has been almost nonexistent. While there are measures available to assess comorbid disorders in people with only ID, the differences in adults with ASD and ID and adults with ID alone may also be a good deal different than in children, and therefore warrants a specialized scale to measure symptoms of ASD in this population. Through research, it is recognized that persons with ASD and ID often evince concomitant psychopathology; yet, the topic has not been systematically studied. The Autism Spectrum Disorders-Comorbidity for Adults (ASD-CA) was designed to screen symptoms of psychopathology that occur more commonly with ASD/ID in adults. The objective of this study was to assess the reliability of the ASD-CA in a first attempt to establish the test's psychometric properties. Three forms of reliability (inter-rater, test-retest, and internal consistency), item analysis, and a factor analysis were conducted.

Psychiatric and psychosocial problems in adults with normal-intelligence autism spectrum disorders

BMC Psychiatry, 2009

Background: Individuals with autism spectrum disorders (ASDs) often display symptoms from other diagnostic categories. Studies of clinical and psychosocial outcome in adult patients with ASDs without concomitant intellectual disability are few. The objective of this paper is to describe the clinical psychiatric presentation and important outcome measures of a large group of normalintelligence adult patients with ASDs.

Brief Report: Adults with Mild Autism Spectrum Disorders (ASD): Scores on the Autism Spectrum Quotient (AQ) and Comorbid Psychopathology

Journal of Autism and Developmental Disorders, 2008

While knowledge about symptom presentation of adults with mild ASD, including comorbid psychopathology, is limited, referral of adults with suspected mild PDD is increasing. We report on pilot research investigating whether patients diagnosed with mild ASD (n = 15) and patients who were not diagnosed with ASD (n = 21) differed in terms of (a) AQ scores and (b) Axis I and II disorders, assessed by the SCAN and the IPDE. Additionally, AQ scores were compared with those from non-ASD patients referred to a general outpatient clinic (n = 369). The results showed very few differences between ASD patients and non-ASD patients. Self-report may not differentiate mild ASD patients from non-ASD patients and Axis I and II disorders seem equally prevalent among these two groups.