Hemocompatible Biofunctionalized magnetic composites for blood detoxification techniques (original) (raw)

Abstract

Biofunctionalized magnetic composites have been obtained by immobilization of biotin via activation with 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide hydrochloride (EDAC) on chitosan-magnetite based particles. FT-IR and TEM analyses confirmed that biotinylated particles have been successfully prepared. Dynamic light scattering measurements showed that bio-functionalized particles have sub-micron size. These particles exhibit a superparamagnetic behavior and good magnetic saturation, characteristics that recommend them for

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