IMMUNOMODULATORY ACTIVITY OF PROBIOTICS AGAINST SALMONELLA TYPHIMURIUM INFECTED MICE (original) (raw)

In this study Wistar albino rats were chosen to evaluate the effectiveness of probiotic therapy. They were induced with infection using known bacterial pathogen Salmonella typhimurium. They were treated separately with common probiotics such as Lactobacillus acidophilus, Streptococcus faecalis, Bacillus megaterium and mixed culture of probiotics. The results of immunomodulatory activities have been found. The reason behind that may be the ways and means how the organisms accommodate and accustom to the intestinal environment and the production of various metabolites attributed to be a protective agents. Being immunomodulatory agent and nontoxic in nature have made these agents more useful as therapeutic agents or as supplements.