Analytical methods for simultaneous estimation of multi-component formulations: a mini review (original) (raw)

Abstract

The pharmaceutical formulations for human use are required to meet standards which relate to their safety and efficacy. The evaluation of safety and efficacy of multi-component pharmaceutical formulations is dependent upon the existence of adequate methods for quality control of the product. Simultaneous estimation methods are now being used more frequently for estimation of drugs in multi-component pharmaceutical formulations due to their inherent advantages such as avoid time consuming extraction and separation; and are economical. For the estimation of multi-component formulation, the instrumental techniques, which are commonly employed, are UV spectrophotometry, gas liquid chromatography, high performance thin layer chromatography, and high performance liquid chromatography. These methods are based upon the measurement of specific and non-specific physical properties of the substances. Chromatographic separation techniques are one of the most widely used techniques for analysis ...

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