Investigations on some chemical indices in blood of quails (Coturnix coturnix) after experimental acute intoxication with the carbamate insecticide carbofuran (original) (raw)

Experiments for monitoring of changes in blood levels of some chemical indices were carried out in quails (Coturnix coturnix) after acute intoxication with the carbamate insecticide carbofuran (Carbosan 35 СТ). The studies involved one control and 4 experimental groups of quails. They were treated orally by increasing single doses of the tested pesticide via oesophageal probe: 1.05 mg/kg (experimental group I), 2.1 mg/kg (experimental group II), 5.25 mg/kg (experimental group III) and 10.5 mg/kg (experimental group IV), corresponding to 1/10 LD50, 1/5 LD50, 1/2 LD50 and LD50  oral doses for albino rats, respectively. In 3 consecutive days prior to the treatment (hours-48,-24 and 0) and on post treatment hours 1, 3, 5, 7, 24 and 48 hours from all groups there after were obtained blood samples from v. subcutanea ulnaris or v. metatarsea medialis for analysis of blood glucose, total bilirubin, total protein, cholesterolе, triglycerides, creatinine and uric acid. It was established that the tested organocarbamate insecticide caused increased the levels of blood glucose, total bilirubin, total protein, cholesterolе, triglycerides and uric acid.