Evaluation of Phytochemical Constituents and Antioxidant Property of Leaf Acetone Extracts of Five Herbaceous Medicinal Weeds (original) (raw)

2019, Journal of pharmaceutical Sciences and Research

In the recent era, medicinal weeds are receiving massive attention for their therapeutic efficacy on different oxidative stress-related diseases. In the present study, five common medicinal herbaceous weeds of West Bengal, and India namely; Heliotropium indicum, Tridax procumbens, Cleome rutidosperma, Commelina benghalensis, and Euphorbia hirta have been chosen from five different families e.g., Boraginaceae, Asteraceae, Cleomaceae, Commelinaceae, and Euphorbiaceae, respectively to decipher their phytochemical, and anti-oxidant properties. The research investigations have concluded that Euphorbia hirta possesses a significant amount of phytochemicals, and it exhibits the highest anti-oxidant activities in comparison with the other four medicinal weeds. Euphorbia hirta leaves acetone extract showed the highest content of extractive value (11.88±0.21%), polyphenols (191.28±2.42 mg Gallic acid equivalent/g dry tissue), flavonoids (60.80±1.22 mg Quercetin equivalent/g dry tissue), tannins (17.84±0.23 mg Tannic acid equivalent/g dry tissue), and polysaccharides (206.73±1.37 mg Dextrose equivalent/g dry tissue), that supports their anti-oxidant property, i.e., inhibitory concentration (IC%) value for ABTS (58.57±0.29%), DPPH (59.17±0.45%) and H 2 O 2 (60.17±0.26%) radical scavenging assays. In Euphorbia hirta leaves acetone extract highest amount of phytochemicals were detected by qualitative assays. The bioactive compounds and anti-oxidant activities are well correlated among each other.