Glucose Catabolism in Cancer Cells: Amplification of the Gene Encoding Type II Hexokinase1 (original) (raw)

An Unusual High-Km Hexokinase Is Expressed in the mhAT3F Hepatoma Cell Line

Armelle Leturque

Journal of Biological Chemistry, 1998

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Differences in expression and intracellular distribution of hexokinase isoenzymes in rat liver cells of different transformation stages

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Hexokinase expression in liver preneoplasia and neoplasia

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Microheterogeneity of cytosolic and membrane-bound hexokinase II in Morris hepatoma 3924A

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The Biochemical journal, 1994

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Glut-1 and hexokinase expression: relationship with 2-fluoro-2-deoxy-D-glucose uptake in A431 and T47D cells in culture

William Eckelman

Cancer Research, 1999

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Regulation of hexokinase and glucose-6-phosphate dehydrogenase genes expression at norm and pathology

Rostyslav Marunych

Biopolymers and Cell, 2013

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Localization of the type III isozyme of hexokinase at the nuclear periphery

ana preller

Archives of Biochemistry and Biophysics, 1992

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Hepatocellular glycogenosis and related pattern of enzymatic changes during hepatocarcinogenesis

P. Bannasch

Advances in Enzyme Regulation, 1984

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The decrease of glycolytic enzyme hexokinase 1 accelerates tumor malignancy via deregulating energy metabolism but sensitizes cancer cells to 2-deoxyglucose inhibition

chih-wei Chen

Oncotarget, 2018

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Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer

Abhishek Jha

Cancer Cell, 2013

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Frequent alteration of the protein synthesis of enzymes for glucose metabolism in hepatocellular carcinomas

Mitsugi Shimoda, Takayuki Shimizu

Journal of Gastroenterology, 2013

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Liver Glycogen Synthase but Not the Muscle Isoform Differentiates between Glucose 6-Phosphate Produced by Glucokinase or Hexokinase

Emili Cid Roldos

Journal of Biological Chemistry, 2002

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One-Step Purification of a Fully Active Hexahistidine-Tagged Human Hexokinase Type I Overexpressed in Escherichia coli

Deborah Agostini

Protein Expression and Purification, 2001

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The Role of Mitochondrial Hexokinase in Neoplastic Phenotype and Its Sensitivity to Lonidamine a

nicola perrotti

Annals of the New …, 1988

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Hexokinase isoenzymes in normal and cirrhotic human liver: suppression of glucokinase in cirrhosis

Loranne Agius

Biochimica et Biophysica Acta (BBA) - General Subjects, 1998

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Subcellular Localization of Hexokinases I and II Directs the Metabolic Fate of Glucose

James Weiss

PLoS ONE, 2011

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Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin

Veronique Nogueira

Nature communications, 2018

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The interaction among glucose transport, hexokinase, and glucose-6-phosphatase with respect to 3H-2-deoxyglucose retention in murine tumor models

Carol Nelson

Nuclear Medicine and Biology, 1996

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Human hexokinase II: localization of the polymorphic gene to chromosome 2

markku lehto

Diabetologia, 1993

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Hexokinase II mRNA and gene structure, regulation by insulin, and evolution

James Tiesinga

Journal of Biological Chemistry, 1993

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Synergistic up-regulation of Hexokinase-2, glucose transporters and angiogenic factors in pancreatic cancer cells by glucose deprivation and hypoxia

Masanobu Kobayashi

Experimental Cell Research, 2007

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Inhibition of mitochondrial and soluble hexokinase from various rat tissues by glucose 1,6-bisphosphate

Rivka Beitner

International Journal of Biochemistry, 1984

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Expression of hexokinase II and Glut-1 in untreated human breast cancer

Ken Zasadny

Nuclear Medicine and Biology, 2002

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The hexose monophosphate shunt in glucose catabolism in ascites tumor cells

Francis Moliterno

Cancer research, 1958

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Hexokinase and glucokinase binding in permeabilized guinea-pig hepatocytes

Loranne Agius

Biochemical Journal, 1994

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Maximum activities of key enzymes of glycolysis, glutaminolysis, pentose phosphate pathway and tricarboxylic acid cycle in normal, neoplastic and suppressed cells

Mary Board

Biochemical Journal, 1990

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A recombinant human'mini'-hexokinase is catalytically active and regulated by hexose 6-phosphates

Mauro Magnani

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Evaluation of hexokinase gene expression in colorectal cancer using bioinformatics tools

Andrew Zaretsky

Biophysics, 2015

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Enzymatic properties of overexpressed human hexokinase fragments

Mauro Magnani

Molecular and Cellular Biochemistry, 1998

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The Catalytic Inactivation of the N-half of Human Hexokinase 2 and Structural and Biochemical Characterization of its Mitochondrial Conformation

Serdal Kirmizialtin

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Metabolic Control of Glycolysis in Normal and Tumor Permeabilized Cells1

Mario Gosalvez Gosalvez

1978

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Elevated hexokinase increases cardiac glycolysis in transgenic mice

Qiangrong Liang

Cardiovascular Research, 2002

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Electrophoretic properties and tissue distribution of multiple forms of hexokinase in various mammalian species

Marc Weksler

Biochemical and Biophysical Research Communications, 1966

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