Evaluation of factors affecting time to achieve dry weight among hemodialysis patients using bioimpedance spectroscopy (original) (raw)

Background Achieving and maintaining dry weight appears to be an effective strategy for controlling and maintaining normotension among hypertensive patients on hemodialysis (HD). Objective The present study aimed to determine the time at which the majority of patients achieve postdialysis dry weight using bioimpedance spectroscopy (BIS). Methods A total of 220 HD patients were prospectively assessed for fluid overload using the Fresenius body composition monitor (BCM). BCM readings were taken at 30 and 45 min postdialysis. Results Among the 220 patients included in this study, 120 (54.5%) achieved a euvolemic state at 30 min, and 25 (11.4%) achieved it at 45 min according to the BCM. In the multivariate analysis, vascular access other than arteriovenous fistula (AVF) (OR = 0.286, p value = 0.049) and cardiovascular disease (OR = 0.384, p value = 0.026) had a statistically significant negative association and receiving HD at Hospital Universiti Sains Malaysia (HUSM) (OR = 2.705, p value = 0.008) had a statistically significant positive association with achieving a euvolemic state at 30 min. Conclusion This suggests that assessing the hydration status at 45 min postdialysis in all patients or in those with identified risk factors for not achieving a euvolemic state at 30 min will provide a relatively accurate assessment for most patients. Strengths and limitations of the study • This study involved heterogeneous group of patients from tertiary-level teaching hospital of Malaysia. • Use of Fresenius body composition monitor (BCM) for dry-weight analysis. • To the best of the authors' knowledge, the current study is strengthened by its prospective nature, and it is the first study to evaluate and suggest the optimal time for dry weight assessments in a clinical setting. • For determining the predictors of achieving a euvolemic state at 30 min, multivariate analysis was conducted. • Nevertheless, a multicenter study with a large sample size and longer follow-up time is needed to confirm the findings of the current study.