The Use of Propolis as Alternative Medicine in Treatment of the Toxicological Insults (original) (raw)
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Recent Studies in the Use of Propolis as a Traditional Medicine: A Review
2020
Propolis is formed by honey bees through mixing a quantity of wax into the resinous substances, which they create by mixing the plant secretions in the pollen baskets on their hind legs with enzymes in their saliva. Depending on the source from which it is obtained, propolis is found in a wide variety of colours, such as yellow, green, dark brown, being solid-state at room temperature. For centuries, apicultural products (such as honey, pollen, propolis, bee venom, bee bread and royal jelly) have been used in traditional medicine for treatment purposes. In recent years, biochemical studies related to propolis have focused on the antimicrobial, anti-inflammatory, antitumoral, and antioxidant activities of propolis.
Experimental Evidence for Therapeutic Potentials of Propolis
2021
Propolis is produced by honeybees from materials collected from plants they visit. It is a resinous material having mixtures of wax and bee enzymes. Propolis is also known as bee glue and used by bees as a building material in their hives, for blocking holes and cracks, repairing the combs and strengthening their thin borders. It has been extensively used since ancient times for different purposes in traditional human healthcare practices. The quality and composition of propolis depend on its geographic location, climatic zone and local flora. The New Zealand and Brazilian green propolis are the two main kinds that have been extensively studied in recent years. Their bioactive components have been found to possess a variety of therapeutic potentials. It was found that Brazilian green propolis improves the cognitive functions of mild cognitive impairments in patients living at high altitude and protects them from neurodegenerative damage through its antioxidant properties. It possess...
Biological activity of bee propolis in health and disease
Asian Pacific journal of cancer prevention : APJCP
Propolis is a natural product derived from plant resins collected by honeybees. It is used by bees as glue, a general-purpose sealer, and as draught-extruder for beehives. Propolis has been used in folk medicine for centuries. It is known that propolis possesses anti-microbial, antioxidative, anti-ulcer and anti-tumor activities. Therefore, propolis has attracted much attention in recent years as a useful or potential substance used in medicine and cosmetics products. Furthermore, it is now extensively used in foods and beverages with the claim that it can maintain or improve human health. The chemical composition of propolis is quite complicated. More than 300 compounds such as polyphenols, phenolic aldehydes, sequiterpene quinines, coumarins, amino acids, steroids and inorganic compounds have been identified in propolis samples. The contents depend on the collecting location, time and plant source. Consequently, biological activities of propolis gathered from different phytogeogra...
Characteristics and uses of propolis
Élelmiszervizsgálati Közlemények
Propolis (bee glue) is an extremely valuable “byproduct” of beekeeping. Its ingredients include many bioactive substances that have a beneficial effect on the human body, which is why propolis has been used by mankind for thousands of years, mainly for medicinal and occasionally cosmetic purposes. Many medicinal and cosmetic products are still produced from the substance today. Its composition varies considerably depending on the geographical location and the health of the producing bees. Its most important components are polyphenolic compounds (phenolic acids, flavonoids, flavonoid esters, diterpenes, sesquiterpenes), lignans, aromatic aldehydes, alcohols, amino acids, fatty acids, organic acids, hydrocarbons, vitamins and minerals. Propolis can be considered a medicinal food. Extracts made from it possess antibacterial, antiviral and antifungal effects. Propolis, in limited quantities, is also suitable for human consumption. The safe dose of propolis for healthy people is 70 mg/da...
Propolis: Properties, Application, and Its Potential
Evidence-Based Complementary and Alternative Medicine, 2013
Propolis is a honeybee product known for its biological and pharmacological properties for centuries. It has been extensively used in traditional medicine and also, because of its antibacterial, antiseptic, anti-inflammatory, and anesthetic activities, in complementary medicine. Propolis became subject of numerous studies developed and carried out all over the world in order to analyze its chemical composition as well as medicinal properties.
Editorial: Therapeutic potential of propolis—from in vitro studies to clinical trials
Frontiers in Pharmacology, 2023
Editorial on the Research Topic Therapeutic potential of propolis-from in vitro studies to clinical trials Propolis is a natural product made by bees from bioactive plant exudates and/or resins, which they employ to protect their colony health and integrity (Ghisalberti, 1979; Simone-Finstrom and Spivak, 2010). Taking their cue from the bees, man has been harvesting and using this product for thousands of years, across many civilizations, stimulated by empirical knowledge concerning its efficacy as a medically useful product (Berretta et al., 2020). More recently, the development of analytical methods and modern extraction processes has led to numerous studies regarding the chemical composition and diversity of propolis, and to a better understanding of its therapeutic properties (Bankova et al., 2019). There are numerous scientific publications showing the antimicrobial, antifungal, antiviral, anti-inflammatory, immunoregulatory, and other biological properties of propolis, especially in vitro and animal models (
Propolis, a resinous beehive product referred as " bee glue " , is collected from various plant sources, such as buds of conifer and poplar trees, by honeybees (Apis mellifera). Honeybees blend this resinous non-toxic substance with their salivary secretions and wax flakes secreted from special glands on their abdomens. Propolis has been used as a healing agent for thousands of years in folk medicine. There is substantial evidence indicating that propolis exhibits a broad spectrum of therapeutic (biological/pharmacological) properties such as antimicrobial, anti-oxidant, anti-inflammatory, immunomodulatory, antitumor, anticancer, antiulcer, hepatoprotective, and cardioprotective properties. Propolis contains more than 200-300 natural compounds. The biological/pharmacological activities of propolis depend on the presence of a large number of polyphenols, mainly flavonoids (flavonoid aglycones), aromatic acids, phenolic acid esters (caffeates and ferulates), triterpenes, diterpenic acids and lignanes. The chemical composition and beneficial properties of propolis vary depending on the plant source, geographic origin and collection time. Present overview is an attempt to discuss the molecular mechanism(s) underlying the diverse biological effects of propolis.
Nutrients
The use of alternative medicine products has increased tremendously in recent decades and it is estimated that approximately 80% of patients globally depend on them for some part of their primary health care. Propolis is a beekeeping product widely used in alternative medicine. It is a natural resinous product that bees collect from various plants and mix with beeswax and salivary enzymes and comprises a complex mixture of compounds. Various biomedical properties of propolis have been studied and reported in infectious and non-infectious diseases. However, the pharmacological activity and chemical composition of propolis is highly variable depending on its geographical origin, so it is important to describe and study the biomedical properties of propolis from different geographic regions. A number of chronic diseases, such as diabetes, obesity, and cancer, are the leading causes of global mortality, generating significant economic losses in many countries. In this review, we focus o...
Indispensable Role of Indian Propolis and its Pharmacological Significance: A Review
Bhartiya Krishi Anusandhan Patrika, Volume 39 Issue 3-4 (September-December 2024) : 223-229, 2024
Honeybees naturally produced a compound called propolis gathered from diverse plant sources. Bees use propolis to build and repair their hives because of its waxy and slimy qualities, which serve as a barrier against outside intruders. It is also a well-known form of folk medicine with a diverse range of biological activities. It has also been used as a health food product in important continental nations including Asia, United States and Europe. Various databased searched in order to find published papers about propolis and its relevant properties. After a thorough evaluation, 4,140 articles were obtained, 2,472 papers in the field of pharmacology of propolis components, 834 articles on the pharmacology and medical therapeutic properties, 65 articles on the propolis component in Indian regions. Propolis is incredibly popular all over the world, but in India propolis research is not widely studied or reported. India, being a vast country, has numerous varieties of propolis differing in chemical compositions and medicinal values. This review gathers major findings on the pharmacological properties of propolis focusing on its antimicrobial, anti-tumor, ant-oxidative and anti-inflammatory properties.