Synthesis, Biological Activity and Spectral Characterisation of Chalcon (original) (raw)

Antioxidants, anti malaria, anti tubercular, antiviral, anti-Inflammatory and antiduretic agents. Some chalcone have been reported as inhibitors of lipoxygenase, beta-secretase(BACEI),cyclogenase, peroxisome. The synthesis of various classes of chalcone and their mode of pharmacological applications have been reviewed. The broad pharmacological applications of chalcones.The case of synthesis and the increased resistance of available chalcones are pharmacologically active compound, it is chemically known as derivatives of 1,3-diphenylprop-2-en-1-one.They have found applications as anticancer, anti-diabetic,anti-HIV, chemotherapeutic agent informed this review. For the preparation of different chalcone products we used magnetic stirring machine to get the solidified product. prepared five different chalcone products namely benzylidene acetophenone, 2,hydroxy benzylidene acetophenone,4,hydroxy benzylidene acetophenone, To determine the functional group, structure and molecular weight .of the chalcones..From FT-IR method the presence of functional groups are analysed, using H 1-NMR spectroscopy number of H atoms are detected ,on the bases of H atoms present in the sample structure of the chalcone is determined and to know the molecular weight of the sample Mass spectroscopy is used.