Targeted Screening of Bioactive Plant Extracts and Phytocompounds Against Problematic Groups of Multidrug-Resistant Bacteria (original) (raw)

2006, Modern Phytomedicine

The use of the medicinal plants in the treatment of human diseases is an age-old practise in traditional systems of medicine throughout the world. Medicinal plants are an important source of diverse bioactive and therapeutic compounds, and the recent increase in the numbers of multidrug-resistant (MDR) bacteria has triggered immense interest in new drugs or preparations from natural sources, including plants. Particularly problematic groups of MDR bacteria include methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), â-lactamase-producing enteric bacteria (E. coli, Salmonella, Klebsiella, Shigella spp.) and other MDR Pseudomonas spp., Campylobacter spp., and Mycobacterium tuberculosis. Excessive and indiscriminate use of antibiotics has led to the development of such drug-resistant bacteria both in hospitals and communities all over the world.

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