Prevalence of sexual dysfunction in patients receiving psychotropic medications (original) (raw)
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Nigerian Journal of Clinical Practice, 2016
Background: Sexual dysfunction is common in patients receiving psychotropic medications and may reduce their quality of life and medication adherence with resultant negative impact on treatment outcomes. Objectives: In this study, we described the various types of sexual dysfunction among psychiatric outpatients receiving psychotropic medications and the sociodemographic and clinical correlates associated with it. Settings and Design: A descriptive, cross-sectional study conducted in a Neuropsychiatric Hospital in Northern Nigeria. Methodology: The participants were made up of a consecutive sample of 255 outpatients attending psychiatric clinic from January to March 2014. Data were collected on sociodemographic items, patient's clinical diagnosis, psychotropic medications received, and duration of treatment. Information about sexual functioning was obtained using the International Index of Erectile Function Questionnaire for the male participants and the Female Sexual Function Index for the female participants. Results: The mean age of the patients studied was 34.7 years (standard deviation [SD] =5.9), with a mean duration of treatment of 3.8 (SD = 6.5) years. Males constituted 47.8% and patients with schizophrenia constituted 43.1%; other diagnoses include bipolar affective disorder, recurrent depressive disorder, and substance use disorder. The prevalence of sexual dysfunction was 64.3%. Age, employment status, and psychotropic medication use were significantly associated with sexual dysfunction; however, only employment status and psychotropic medication use significantly predicted sexual dysfunction. Conclusions: We concluded that sexual dysfunction is highly prevalent among patients receiving psychotropic medication; as such inquiries about sexual function should be routinely carried out by clinicians as this may negatively impact on adherence and quality of life.
Sexual Dysfunction Related to Psychotropic Drugs: A Critical Review Part II: Antipsychotics
Pharmacopsychiatry, 2013
Sexual dysfunction is a potential side eff ect of antipsychotic drugs: this article presents a critical review of the current literature. Although many studies have been published on the subject, only some used a validated sexual function rating scale and most lacked either a baseline or placebo control or both. In addition, many of the studies on sexual dysfunction associated with antipsychotic medication are limited by other methodological fl aws. However, there is consistent evidence to suggest that a large number of antipsychotic drugs adversely aff ect one or
2020
Background: There has been an increase in the prevalence of sexual dysfunction in the general population especially among mentally ill patients. This seems to be neglected problem in low-income countries. This study aims at establishing the prevalence of sexual dysfunction and associated risk factors in mentally ill patients attended at psychiatric outpatient of Dessie Referral Hospital. Method: Institution based cross sectional study was conducted at Dessie Referral Hospital. Interviewer administered questionnaire of socio demographic, morisky adherence questionnaire, PHQ-9, suicidal behavior assessment questionnaires and change in Sexual Functioning Questionnaires were used. Logistic regressions were used further analysis. Result: Prevalence of global sexual dysfunction among patients with mentally illness is 58.2%. It is slightly more prevalent among males (64.1%) than that of females (50.8%). Age, marital status, current substance use, suicidal ideation, type of DSM-5 diagnosis,...
ABSTRACT Sexual satisfaction is one of the major determinant of quality of life. Our main objective of this study is to assess the prevalence of sexual dysfunction in patients receiving Psychotropic drugs, to assess the category of psychiatric diseases more prone to sexual dysfunction and to assess class of psychotropic drugs produces sexual side effects frequently. The study is Open, naturalistic, cross sectional, observational for 6 months in a tertiary care teaching hospital. The data collection was done only once at a single point of time during the study. The data are collected by the use of standard validated questionnaire like DISF (Derogates Interview for Sexual function) male and female translated version duly permitted from the author. And the dates were statistically analysed and evaluated. Thus obtained results were promising for further studies. In male and female patients using psychotropic drugs a significantly higher incidence of sexual dysfunction was observed as ADR. In male and female patients using psychotropic drugs, the quality of life in terms of sexual function was significantly lower by comparing age, sex, marital status matched control group. Antidepressants showed significantly higher incidence of sexual dysfunction in both male and female psychiatry patients followed by antipsychotics and then anxiolytics.
Sexual Dysfunction in Male Patients Taking Antipsychotics
2015
Background: Antipsychotics drugs are known to cause sexual dysfunction and are said to be a major cause of non-compliance /poor compliance. There is no local data on the subject although clinical observations indicate that sexual dysfunction in patients on neuroleptics is relatively common. This study was carried out to ascertain the frequency of sexual dysfunction in patients taking antipsychotics medications as no study has been done locally on the subject. Methods: Sexual dysfunction was assessed in fifty patients receiving antipsychotic medication and fifty normal controls using Arizona Sexual experience scale (ASEX). Results: Erectile dysfunction (48%) and ejaculatory dysfunction (45%) are the two most prominent sexual dysfunction affecting patients taking antipsychotics and the difference from controls is statistically significant. Conclusions: Sexual dysfunction among male patients on antipsychotic medications is relatively common. Key Words: Erectile dysfunction, ejaculatory...
Frequency of Sexual Dysfunction in Patients with a Psychotic Disorder Receiving Antipsychotics
Journal of Sexual Medicine, 2010
Introduction. Although it is a troublesome side effect, information on antipsychotic-induced sexual dysfunction is limited.Aim. To evaluate the frequency of sexual dysfunction and its impact on treatment adherence in patients with a psychotic disorder treated with various antipsychotics under routine clinical conditions.Methods. Subjects included were sexually active male and female patients 18 years of age or older with a diagnosis of schizophrenia, schizophreniform disorder, schizoaffective disorder, or other psychotic disorder. This was a multicenter, cross-sectional, and naturalistic study conducted by 18 investigators. In addition to sexual functioning, we recorded demographic data, psychiatric diagnosis according to the Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition), and medication history.Main Outcome Measure. Pyschotropic-Related Sexual Dysfunction Questionnaire (PRSexDQ-SalSex).Results. All the analyses were performed in the 243 evaluable patients. Most patients were males (71%), and the most common diagnosis was schizophrenia (71%). Overall, 46% of the patients exhibited sexual dysfunction according to the assessment with the SalSex (50% of the males and 37% of the females). Only 37% of the patients with sexual dysfuntion spontaneously reported it. Among the patients exhibiting sexual dysfunction, 32% reported to have poor tolerance to the disturbance. With the exception of conventionals depot, which had a very important and greater effect on females’ sexual funtioning, the severity and tolerance of sexual dysfunction were worse in males than in females regardless of the antipsychotic studied. In the univariate logistic regression analysis, using olanzapine as a reference category, risperidone (odds ratio [OR] 7.45, 95% confidence interval [CI] 3.73–14.89) and conventionals, depot (OR 4.57, 95% CI 1.72–12.13) and nondepot (OR 4.92, 95% CI 1.43–16.93), showed a significant increased risk of sexual dysfunction.Conclusions. Our results show that sexual dysfunction is very common in patients receiving long-term treatment with antipsychotics, and it is associated with a great impact in a substantial proportion of patients. Montejo AL, Majadas S, Rico-Villademoros F, LLorca G, de la Gándara J, Franco M, Martín-Carrasco M, Aguera L, and Prieto N. Frequency of sexual dysfunction in patients with a psychotic disorder receiving antipsychotics. J Sex Med 2010;7:3404–3413.
Psychotropic Drug???Induced Sexual Function Disorders
Drug Safety, 1998
The human sexual response can be divided into 3 phases: desire (libido), excitement (arousal) and orgasm. The fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) classifies sexual disorders into 4 categories: (i) primary; (ii) general medical condition-related; (iii) substanceinduced; and (iv) 'not otherwise specified' sexual dysfunctions. Each of the 4 DSM-IV categories has disorders in all 3 sexual phases. Substance-induced sexual dysfunctions are caused by the use of either substances of abuse [alcohol (ethanol), amphetamines, cocaine, opioids or sedatives/hypnotics/anxiolytics], or prescription medications which include psychotropic drugs. Patients with psychiatric difficulties tend to experience more frequent sexual function disturbances. The literature provides more than anecdotal evidence that psychotropic drugs can induce sexual function disorders in the epidemiologically vulnerable population of psychiatric patients. Sexual dysfunctions caused by psychotropic drugs can be divided into 2 groups: sexual inhibition (inhibited desire, inhibited arousal and inhibited or
Antipsychotics and Sexual Dysfunction: Sexual Dysfunction-Part III
Online Journal of Health and Allied …, 2009
Review: Antipsychotics and Sexual Dysfunction :: Sexual Dysfunction: Part III Anil Kumar MysoreNagaraj, Senior Resident, Dept of Psychiatry ... of Medicine, University of Wollongong, Australia, Satheesh Rao, Professor and Head, Dept of Psychiatry, KS Hegde Medical Academy ...