Pulmonary ct manifestations of COVID-19: changes within 2 weeks duration from presentation (original) (raw)

Role of CT Chest in Evaluation of Pulmonary Manifestations of COVID-19 Recovered Cases

Asian Journal of Pharmaceutical and Clinical Research

Objective: Pulmonary manifestations may be seen in a number of coronavirus disease 2019 (COVID-19)-recovered the evidence on post-COVID pulmonary sequelae is still limited. Herein, we aim to assess the role of computed tomography (CT) chest in the evaluation of pulmonary manifestations of COVID-19 recovered cases. Methods: We conducted a hospital-based study in the Department of Radiodiagnosis at Government Medical College and Rajindra Hospital Patiala. It included 182 reverse transcriptase-polymerase chain reaction (RT-PCR)-proven COVID-19 patients after they recovered from the disease with at least one negative RT-PCR test and/or clinical recovery. Clinical data and CT findings in the recovery phase were summarized, and the relationship of different clinical parameters with CT severity scores was analyzed. Results: The mean (±standard deviation [SD]) age of patients was 50.2±14.7 years, and 62.6% of them were males. The mean (±SD) symptomatic-scan interval was 33.05±22.27 days. Pu...

An Analysis of High-Resolution Computed Tomography Chest Manifestations of COVID-19 Patients in Pakistan

Cureus

The objective of the present study is to describe high-resolution CT (HRCT) chest manifestations of coronavirus disease 2019 (COVID-19) patients presenting to a tertiary healthcare facility in Punjab, Pakistan, and to analyze the distribution of the disease in lung fields. Additionally, we assess the role of chest CT severity scoring (CT-SS) in determining the severity of pneumonia. Methods In this cross-sectional descriptive study conducted from March 30, 2020, to May 30, 2020, 87 confirmed COVID-19 patients undergoing HRCT scan in a tertiary care facility in Punjab, Pakistan were included. The HRCT chest was performed on the patients using a standard protocol. Each study was evaluated for the presence of ground-glass opacities (GGOs), consolidation, mixed pattern, distribution, crazy paving, reverse halo sign, nodules, pleural effusion, and other findings. Additionally, CT-SS was calculated by dividing each lung into 20 zones. Each zone was scored as 0, 1, and 2, representing no involvement, <50% involvement, and >50% involvement of one zone respectively (total score: 0-40 for each patient). The patients were classified into mild, moderate, and severe cases (mild: CT-SS of <20, moderate: CT-SS of 20-30, and severe: CT-SS of >30). Results GGO was the most common finding, as seen in 88.5% of the patients, followed by consolidations (52.8%) and crazy paving (33.3%). The majority of the patients showed the bilateral and peripheral distribution of the disease process. Vascular dilatation and bronchiectasis were seen in 10 patients; pleural effusions were observed in only two study patients, while no patient exhibited reverse halo sign or pulmonary nodules. The superior segment of lower lobes was the most commonly involved segment bilaterally. According to CT-SS, 78 (89.6%), six (6.9%), and three (3.45%) patients had mild, moderate, and severe disease respectively. Conclusion The typical imaging findings of COVID-19 on HRCT are GGOs with multilobe involvement and bilateral, peripheral, and basal predominance. CT-SS is helpful in categorizing pneumonia into mild, moderate, and severe types, thereby helping to identify patients with severe disease. This is particularly helpful in settings where fast triage is required.

Radiological profile of patients undergoing Chest X-ray and computed tomography scans during COVID-19 outbreak

Pakistan Journal of Medical Sciences, 2021

Background & Objective: Radiology has played a significant role in the diagnosis and quantifying the severity of COVID 19 pulmonary disease. This study was conducted to assess patterns and severity of COVID-19 pulmonary disease based on radiological imaging. Methods: A prospective observational study was conducted in a large tertiary care public sector teaching hospital of Karachi, Pakistan from June 2020 till August 2020. All confirmed and suspected COVID-19 patients referred for chest X-rays and computed tomography (CT) scans were evaluated along with RT-PCR results. Suspected patients were followed for RT-PCR. Radiological features and severity of imaging studies were determined. Results: Of 533 patients in whom X-rays were performed, majority had severe/critical findings, i.e., 304 (57.03%). Of 97 patients in whom CT scan was performed, mild/moderate findings were observed in 63 (64.94%) patients. Of 472 patients with abnormal X-rays, majority presented with alveolar pattern 459...

Chest CT Findings after 4 Months from the Onset of COVID-19 Pneumonia: A Case Series

Diagnostics, 2020

Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although the reference standard for SARS-CoV-2 diagnosis is real-time reverse transcription polymerase chain reaction (RT-PCR), computed tomography (CT) is recommended for both initial evaluation and follow-up. There is a growing body of published evidence about CT evolution during the course of COVID-19 pneumonia. Here, we report six confirmed cases of COVID-19 patients who underwent unenhanced chest CT on admission and after 4 months from the onset of symptoms. Chest-CT at first admission showed the typical CT features of COVID-19. Interestingly, the follow-up CT revealed the persistence of lung abnormalities in five cases even if all the patients were completely asymptomatic. Further studies are needed for a comprehensive understanding of the disease progression and the resulting late imaging modifications.

Temporal evolution of tomographic findings of pulmonary infection in COVID-19

einstein (São Paulo), 2020

Letter to the editor: Dear Editor, We very enthusiastically read the excellent review article entitled “COVID-19 findings identified in chest computed tomography”, by Rosa et al.,(1) published in the last issue of this journal. This manuscript shows the relevance of chest computed tomography (CT) in detecting the pulmonary manifestations of the coronavirus disease 2019 (COVID-19), presenting cases in a very didactic manner, but not discussing its role in the follow-up of the disease. Although we know this was not the scope of the authors, we would like to complement this discussion with some topics related to the impact of this imaging method in the prognosis and progression (long-term follow-up) of COVID-19.

Chest CT findings in COVID 19 disease in relation with duration of illness: A study of two hundred cases

Central Medical College Journal

Chest CT scans of 200 symptomatic patients infected with COVID 19 from different health facilities and home were reviewed for common CT findings in relationship with their clinical symptoms, comorbidities and the time between symptom onset and the initial CT scan was studied in this cross-sectional study. Cases were categorized into three groups according to the timing of HRCT, 10 cases were in early (0-2days), 56 cases in intermediate (3-5days) and 110 cases were in late (6-12days) groups. Chest CT scan images showed bilateral peripheral ground glass opacities 96.63%, pulmonary consolidations 15.9%. Notably 29.54% patient had normal CT scan chest and 60% of them were imaged at early phase. With a longer duration of symptoms, chest CT findings were more typical including GGO, consolidation with greater total lung involvement. Bilateral peripheral GGO was observed in 20% patients at early phase while 53.57% and 64.54% were observed at intermediate and late phase of illness. Among the...

Chest Computed Tomographic Imaging Findings and Clinical Criteria of COVID-19 in Zagazig University Hospitals, Egypt

Zagazig University Medical Journal, 2021

Background: COVID-19 pneumonia patients have variant prognosis and mortality. A great concern should be given to the clinical and imaging characteristics of those patients, As a result, the aim of current research was to identify clinical, laboratory, and chest computed tomography results in confirmed COVID-19 patients, as well as to compare severe patients to non-severe groups. Methods: In a retrospective cross-sectional analysis, 169 confirmed COVID-19 individuals were enrolled. Computerized medical reports and images were used. Results: The enrolled individuals were classified into asymptomatic: 2 patients (1.2%), mild: 33 patients (19.5%), moderate: 103 patients (60.9%) and severe: 31 patients (18.3%). Fever, cough, shortness of breath were significantly more frequent symptoms in severely infected COVID patients (p=0.001). Moreover, a highly significant decrease in SPO2(p=0.00), a remarkable increase in WBCs (p=0.002), and a significant increase in CRP and Ferritin were detected in that group (p=0.00). The chest "high resolution computed tomography findings were associated with multiple lesions in both lungs and more GGO with consolidation (p<0.05). Crazy pavement, septal thickening, and subpleural thickening were also significantly presented in severe COVID pneumonia rather than other groups (p<0.05). Conclusion: Occurrence of clinical factors including aging, cough, fever, dyspnea, comorbidities, hypoxemia, increased WBCs, increased CRP, and ferritin were more prevalent in severe COVID-19 pneumonia. GGO with consolidation and Septal thickening were independent predictors of COVID pneumonia severity findings in HRCT.The use of computed tomography in the diagnosis and assessment of illness severity is crucial.

Computed tomography imaging findings in hospitalized patients with coronavirus disease 2019 (COVID‑19): a descriptive study of 81 cases

Polish Journal of Radiology, 2021

Purpose: Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) has proven to be a diagnostic challenge. Early studies have shown that computed tomography (CT) imaging may be useful in diagnosis of these patients. We aim to report CT findings in a series of hospitalized patients. Material and methods: A total of 81 patients were included in this study. All of the patients were hospitalized and had SARS-CoV-2 infection proven by molecular assay. All patients had a CT scan on the first day of admission. Imaging results were reviewed by two separate radiologists, and imaging findings were documented. Results: Seventy-eight patients had abnormal CT imaging, while 3 had normal CT imaging. The sensitivity of CT in diagnosing coronavirus disease 2019 (COVID-19) was estimated to be 96%. The most common imaging finding was ground glass opacities, followed by septal thickening. Most lesions were located at the periphery and posterior of the lungs. Most lesions were multifocal, and involved the right lower lobe more frequently. Chest X-rays were normal in 38 patients, and the sensitivity of chest X-ray in diagnosing SARS-Cov-2 was 54%. Conclusions: CT scans could be used in diagnosis of patients with a high sensitivity (93%). No common imaging findings may also be seen alongside ground glass opacities, based on the degree of disease progression.