A comparative study of effect of oral chronic cyanide administration on some rabbit tissue ATPases (original) (raw)

Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology, 1994

Abstract

The effect of oral KCN administration on Na(+)-K(+)-ATPase, Ca(2+)-ATPase and Mg(2+)-ATPase activities was studied in some rabbit tissues. Generally, the order of activity of the enzymes was kidney > liver > ileum > colon. There were significant decreases (P < 0.05) in the activities of all the ATPases in the tissues of KCN-treated rabbits relative to controls. The decreases in Na(+)-K(+)-ATPase and Ca(2+)-ATPase activities were most pronounced in liver and kidney. The decreases in ATPases suggest impairment of membrane function as a result of the toxic effect of cyanide.

N. Okolie hasn't uploaded this paper.

Let N. know you want this paper to be uploaded.

Ask for this paper to be uploaded.