Analysis of the tendon cell fate using Scleraxis, a specific marker for tendons and ligaments (original) (raw)

This paper explores the role of Scleraxis, a tendon- and ligament-specific marker, in tendon cell fate determination during development. The study highlights the significance of molecular signaling pathways, particularly BMP and Noggin, in regulating Scleraxis expression and subsequently impacting tendon morphogenesis. The research offers insights into the complex interactions between tendon markers and their developmental context, providing a deeper understanding of tendon biology and potential implications for regenerative medicine.