Multiphasic multidetector computed tomography study of a rare tracheal tumor: granular cell tumor (original) (raw)
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Diagnostic Cytopathology, 2000
We report on a case of extraluminal tracheal granular-cell tumor which was interpreted as a Hurthle-cell neoplasm of the thyroid on fine-needle aspirate. Review of the literature reveals only one other such case. The patient was a 35-yr-old female who presented with an enlarged thyroid. Aspiration cytology revealed a syncytium of cells with abundant granular cytoplasm interpreted as a thyroid follicular neoplasm with Hurthle-cell change. However, histology of the resection specimen with immunohistochemistry confirmed it as a granular-cell tumor. The cytologic differential diagnosis of neoplasms with oncocytoid cytoplasm in and around the thyroid should include granular-cell tumor of the trachea.
Pediatric granular cell tumor of the tracheobronchial tree
Journal of Pediatric Surgery, 2008
Granular cell tumors are lesions of neural crest origin with a predilection for the skin and soft tissue. Granular cell tumors of the tracheobronchial tree are exceedingly rare in the pediatric population, with only 5 reported cases. All 5 of these lesions presented within the cervical trachea. We report a large granular cell tumor in the posterior mediastinum, densely adherent to the intrathoracic tracheal carina.
Granular cell tumour of the larynx - A case report
Ghana Medical Journal, 2016
Granular cell tumours (GCTs) are benign tumours rarely found in the larynx even though they are common in the head and neck region. The laryngeal tumour may be asymptomatic but typically patients present with hoarseness of voice, stridor, haemoptysis and dysphagia. The lesion can mimic squamous cell thus deep biopsy must be taken with adjacent normal tissue to confirm this pathology. Immunohistochemical staining is also used. Complete surgical resection of this tumour is the treatment of choice. We present a 25 year old woman with a laryngeal granular cell tumour involving the right vocal cord diagnosed after direct laryngoscopy and biopsy. She was treated by right cordectomy via a laryngofissure approach. We present the case due to the rarity of the laryngeal granular cell tumour and the need to highlight the importance of taking deep biopsies. If biopsies are superficial, an inexperienced pathologist would mistake it for well differentiated carcinoma.
Granular cell tumor on the larynx
2020
Granular cell tumors (GCTs) are neoplastic lesions rarely seen in adults. GCTs are most commonly found in the head and neck region, and exceptionally on the larynx. Laryngeal GCTs symptoms and signs may manifest as hoarseness, dysphagia, coughing, hemoptysis, and stridor. We report a case of a 36-year-old woman, who complained of dysphonia. Her clinical history, pathological findings, and treatment are addressed in this article.
Multi-focal, multi-centric granular cell tumours: a management dilemma
Respirology Case Reports
Granular cell tumours (GCT) are uncommon, usually solitary tumours of neural/Schwann cell origin that occur at any site of the body, and typically run an indolent clinical course. Treatment by excision is recommended. Distant or nodal metastases are the only reliable signs of malignancy. We describe the case of a 47-year-old woman with a multi-focal, multi-centric GCT involving the pulmonary and gastrointestinal systems, highlighting the imaging and pathological features and the challenge faced in establishing its malignant potential.
International Journal of Medical Imaging, 2015
Bronchogenic carcinoma is one among the leading causes of death in males in India and globally. Multidetector row Computed Tomography is a non-invasive technique for evaluation of bronchogenic carcinoma. Aims and objections: To document imaging characteristics of various histopathological cell types of bronchogenic carcinoma by MDCT and to correlate with histopathology. A prospective study was done on 60 patients with clinical or radiological suspicion of bronchogenic carcinoma undergoing MDCT. The final diagnosis was established by histopathology. Study duration was for 2 years from January 2013 to December 2014. Results: MDCT is a promising tool in evaluation of bronchogenic carcinoma. Squamous cell carcinoma is the most common histological celltype, closely followed by adenocarcinoma. Hilar mass was the predominant presentation followed by lung mass.