original ) (raw )Impact of P-glycoprotein at the blood-brain barrier on the uptake of heroin and its main metabolites: behavioral effects and consequences on the transcriptional responses and reinforcing properties
marianne seleman
Psychopharmacology, 2014
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Screening of multidrug-resistance sensitive drugs by in situ brain perfusion in P-glycoprotein-deficient mice
Salvatore Cisternino
Pharmaceutical research, 2001
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Lack of evidence for involvement of P-glycoprotein in brain uptake of the centrally acting analgesic, tramadol in the rat
Behjat Sheikholeslami
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques, 2012
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Identification of P-glycoprotein substrates and inhibitors among psychoactive compounds – implications for pharmacokinetics of selected substrates
amal sebastian
Journal of Pharmacy and Pharmacology, 2004
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Antiepileptic drugs modulate P-glycoproteins in the brain: A mice study with 11C-desmethylloperamide
Lieselotte Moerman , Robrecht Raedt
Epilepsy Research, 2011
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The role of P-glycoprotein in blood-brain barrier transport of morphine: transcortical microdialysis studies inmdr1a (−/−) andmdr1a (+/+) mice
Elizabeth CM de Lange
British Journal of Pharmacology, 1999
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PET Studies on P-glycoprotein function in the blood-brain barrier: how it affects uptake and binding of drugs within the CNS
Aren van Waarde
2004
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The role of P‐glycoprotein in blood‐brain barrier transport of morphine: transcortical microdialysis studies in mdr1a (−/−) and mdr1a (+/+) mice
Elizabeth CM de Lange
British journal of …, 1999
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P-glycoprotein Modulates Morphine Uptake into the CNS: A Role for the Non-steroidal Anti-inflammatory Drug Diclofenac
Thomas Davis
PLoS ONE, 2014
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The transport of antiepileptic drugs by P-glycoprotein
Larry Baum
Advanced Drug Delivery Reviews, 2012
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Effect of P-glycoprotein modulation on the clinical pharmacokinetics and adverse effects of morphine
Juergen Drewe
British Journal of Clinical Pharmacology, 2000
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Opioid Transport by ATP-Binding Cassette Transporters at the Blood-Brain Barrier: Implications for Neuropsychopharmacology
Salvatore Cisternino
Current Pharmaceutical Design, 2011
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P-glycoprotein Interactions of Novel Psychoactive Substances - stimulation of ATP consumption and transport across Caco-2 Monolayers
Hans Maurer
Biochemical pharmacology, 2015
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Pharmacokinetics of P-glycoprotein inhibition in the rat blood-brain barrier
Obaidur Rahman
Journal of Pharmaceutical Sciences, 2008
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Utility of unbound plasma drug levels and P-glycoprotein transport data in prediction of central nervous system exposure
L. Cohen , Gino Salituro
Xenobiotica, 2009
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THE ROLE OF THE POLYMORPHIC EFFLUX TRANSPORTER P-GLYCOPROTEIN ON THE BRAIN ACCUMULATION OF d-METHYLPHENIDATE AND d-AMPHETAMINE
Haojie Zhu
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G protein-coupled receptor (GPCR) trafficking in the central nervous system: relevance for drugs of abuse
Wes Kroeze
Drug and Alcohol Dependence, 1998
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The effect of quinidine, a strong P‐glycoprotein inhibitor, on the pharmacokinetics and central nervous system distribution of naloxegol
Khanh bui
The Journal of Clinical Pharmacology, 2015
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Species Comparison of In Vivo P-Glycoprotein-Mediated Brain Efflux Using mdr1a-Deficient Rats and Mice
Christoffer Bundgaard
Drug Metabolism and Disposition, 2012
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P-glycoprotein is not involved in the differential oral potency of naloxone and naltrexone
Youssef Daali
Fundamental & Clinical Pharmacology, 2009
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In-vitro respiratory drug absorption models possess nominal functional P-glycoprotein activity
Pavel Dolezal
Journal of Pharmacy and Pharmacology, 2009
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Effect of chronic exposure to morphine on the rat blood-brain barrier: focus on the P-glycoprotein
Bruno Saubaméa
Journal of Neurochemistry, 2008
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In Vitro P-glycoprotein Assays to Predict the in Vivo Interactions of P-glycoprotein with Drugs in the Central Nervous System
selene maia de morais
Drug Metabolism and Disposition, 2007
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