Intraperitoneal fluid accumulation induced by Clostridium perfringens alpha-toxin (phospholipase C) (original) (raw)

Intraperitoneal fluid accumulation induced by Clostridium perfringens alpha-toxin (phospholipase C)

Acta microbiologica Polonica, 2002

Abstract

We report that the intraperitoneal injection of Clostridium perfringens alpha-toxin into mice induces ascites. This phenomenon was monitored by measuring fluid volume and analyzing hematologic data. The mouse toxicity test provides a simple and useful model for examining C. perfringens alpha-toxin-induced vascular permeability.

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