A two-phase kinetic model for fungal growth in solid-state cultivation (original) (raw)
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A survey of computational and physical methods applied to solid-state fermentation
Applied Microbiology and Biotechnology, 2004
During the last decade, significant effort has been made to apply computational and physical methods to solid-state fermentation (SSF). This had positive impact both on our understanding of the basic principles underlying this old technology, and on the latest progress made in industrial bioengineering. Guidelines on bioreactor design and operation including scale-up, new methods for biomonitoring and advanced control strategies are among the most important outcomes of practical use. Nevertheless, there still is a lack of experimental data, which hampers parameter identification and thus broader use of mathematical modeling. More attention should therefore be paid to combining and concentrating modern physical techniques and computational approaches in order to allow better model validation and thus further progress in rational bioengineering of SSF.
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Enzyme and Microbial Technology, 2006
The growth and sporulation of Mucor bacilliformis on an inert solid support (polyurethane foam) were studied at different conditions of water content and nutrient concentration. Maximum biomass (0.59g/ginertsupport) and spore production (6×108spores/ginertsupport) were obtained for the highest water content (90%, w/w) and the most concentrated medium studied. The growth, CO2 production and carbon source consumption of M. bacilliformis were modeled
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