Detection of Hepatocelluar Carcinoma in MR Arterial Portography; Diagnostic Significance as a Pre-Operative Evaluation (original) (raw)
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[An autopsied case of primary pulmonary hypertension complicated by hepatopulmonary syndrome]
PubMed, 1995
A 57-year-old man, who had received a transfusion five years before, was admitted to our hospital complaining of worsening dyspnea on exertion. Cardiac catheterization was performed, and pulmonary hypertension was diagnosed. Liver dysfunction was also documented. We administered diuretics and observed his clinical course. Gradually worsening hypoxemia and radioisotope accumulation in the kidney following a lung perfusion scintigram suggested the existence of an intrapulmonary shunt. The patient died seven years later due to exacerbation of heart failure secondary to pulmonary infection. Autopsy revealed remarkable hypertensive pulmonary arteriopathy as well as abnormal dilation of precapillary pulmonary arterioles. Esophageal varices suggested portal hypertension. Marked hypoxemia and intrapulmonary vascular dilation suggest the contribution of an hepatopulmonary syndrome.
Journal of Laboratory Medicine and Quality Assurance
Background: Commutability is essential to harmonize different measuring systems and to evaluate the performance of participating laboratories in external quality assessment (EQA). This study aims to assess the commutability of EQA materials in the tumor marker program of the Korean Association of External Quality Assessment Service. Methods: We analyzed commercial quality control (QC) materials, individual patient samples, and frozen human serum pools (FSPs) based on the Clinical and Laboratory Standards Institute guidelines. Alpha-fetoprotein (AFP), carcinoembryonic antigen (CEA), and total prostate-specific antigen (PSA) were assayed in triplicate in all samples using four analytical systems at the three laboratories. The results obtained from pairs of assays were plotted and assessed using Deming regression analysis. The criterion for commutability was a 95% prediction interval, and bias for noncommutability was calculated. Results: FSPs were commutable in all AFP, CEA, and total PSA assay methods. Bias for AFP, CEA, and total PSA ranged from-203% to 27%,-67% to 45%, and-9% to 12%, respectively. Commercial QC materials for AFP and PSA were commutable in four assays, whereas for CEA, noncommutability was observed. Conclusions: Our results validated that the frozen serum pools were commutable across different platforms for tumor marker assays. Therefore, validation findings from materials like FSPs and information about their commutability needs to be reported, for the applicability of EQA programs.
Carotid Cavernous Fistula: Role of Open Surgery in The Era of Endovascular Treatment
Nepal Journal of Neuroscience, 2017
A 18-year-old right handed girl presented with progressive proptosis, chemosis, diplopia and an orbital bruit of right eye, 3 days after alleged history of fall from a tree, The intraocular pressure was increased. The suspected diagnosis of a direct carotid cavernous fistula (CCF) was confirmed by CT angiography CT Angiography showed direct fistulous communication of cavernous segment of right internal carotid artery with right cavernous sinus (type A right CCF) and linear minimally displaced fracture of right zygomatic arch and linear undisplaced fracture of wall of right orbit. The patient underwent right pterional craniotomy and transcavernous occlusion of fistula of right internal carotid artery (ICA). Surgery was performed with gradual resolution of the symptoms and normalization of the intraocular pressure.The pathogencsis, symptomatology, treatment of carotid cavernous fistulas are discussed.Nepal Journal of Neuroscience, Volume 14, Number 1, 2017, Page: 36-39
Evaluation of the Performance of Lumipulse G1200 for Tumor Marker Assays
Laboratory Medicine Online, 2012
G1200 (Fujirebio, Tokyo, Japan)이 국내에 도입되었다. 저자들은 종양표지자인 carcinoembryonic antigen (CEA), α-fetoprotein (AFP), cancer antigen 125 (CA125), cancer antigen 15-3 (CA15-3), cancer antigen 19-9 (CA19-9), prostate specific antigen (PSA), protein induced by vitamin K absence or antagonist-II (PIVKA-II),
Clinical Guideline for the Diagnosis and Treatment of Cardiovascular Infections
Infection and Chemotherapy, 2011
There are many various diseases in the cardiovascular infections, and we tried to make a diagnosis and treatment guideline for several diseases which can be experienced by physician at clinical setting. Infective endocarditis (native and prosthetic valve), myocarditis, pericarditis, suppurative thrombophlebitis, and infective endarteritis and mycotic aneurysm are included in this guideline.
CT and angiographic findings in ruptured intracranial aneurysms
Journal of the Korean Radiological Society
Oepa rtm en t of Radiology, College o(Medicine, Chonnarn National Un i vers ity CT has beco l1l e th e 11l 0sl usef 비， non.in vasive diagnostic l1l ethod ðS th e initial eXð l1l inatio n in the diagnosis of ruptured intracranial aneurysrn with intracrania! hell1orrhage(subarachnoid , intracerebral and in traventricular hemorrhage), hydrocephalus and infarclion Furthermore, high resolulion CT ca n uernonstrale aneurysrn ilself But angiography is the lasl and conc lusi ve rnethod as yel , ior better eva luati on oí vascula r anatornic struc. ture of aneurysrn for surgery Auth ors anJlyzed 40 cas es of ruptured intracranral dneurys l11 confirl1l ed by CT, angiography and/or surge ry at Chonnarn Nationa l University Hospital from July. 83 ' lo Jul y, 85'
American Heart Journal, 1991
Background and Objectives: Some reports have suggested that coronary microvascular dysfunction plays a role in the recovery of myocardial function in patients with obstructive coronary artery disease. Thrombolysis in myocardial infarction (TIMI) frame count (TFC) is regarded as a simple, reliable method for evaluating microvascular function. We evaluated microvascular function using TFC immediately after coronary intervention and compared TFC with left ventricular systolic function eight months later. Subjects and Methods: We studied 68 patients with obstructive coronary artery disease who underwent coronary intervention. Just after intervention, TFC was calculated with the standard method. Left ventricular systolic function was assessed with left ventricular diastolic dimension (LVEDd), ejection fraction (EF), and wall motion score index (WMSI). Eight months after intervention, we completed follow-up coronary angiography and echocardiography. We defined high TFC (HTFC) as a TFC greater than 18. Results: Ten patients were in the HTFC group, and 58 patients were in the low TFC (LTFC) group. There was no difference between the two groups with regard to baseline cardiovascular characteristics and angiographic findings. Just after intervention, the HTFC group showed significantly higher LVEDd (56.6±8.9 mm) and WMSI (1.60±0.65) compared to the LTFC group (50.3±5.9 mm, p<0.05; 1.34±0.29, p<0.05, respectively), but there was no significant difference in EF between the groups (49.3±18.6% vs. 56.2±14.8%, p> 0.05). Eight months after intervention, there was also a significant decrease in the WMSI in the LTFC group (1.23±0.25, p<0.05), but not in the HTFC group (1.57±0.62, p>0.05). Conclusion: Increased TFC immediately after coronary intervention is an important poor prognostic factor related to myocardial systolic function eight months after coronary intervention. Coronary microvascular dysfunction may influence myocardial recovery in the setting of obstructive coronary artery disease.