In vitro characterisation of zirconia coated by bioactive glass (original) (raw)
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Glass coatings on zirconia with enhanced bioactivity
Journal of the European Ceramic Society, 2016
Highly bioactive glass coatings were successfully achieved by applying a newly developed bioactive glass layer having a low Ca/P ratio on a ZrO 2-3%Y 2 O 3 ceramic substrate. The thermal properties of the glass allowed covering zirconia substrates both by amorphous and glass-ceramic coatings. The coatings exhibited 345 m thickness and were free from surface cracks, highlighting the good compatibility between the glass and the substrate in terms of expansion coefficient matching. The synthesized materials achieved the formation of a crystalline carbonate apatite layer after 3 days soaking in SBF solution. Although the slight diffusion of the amorphous and glass-ceramic coatings through the ZrO 2-3%Y 2 O 3 support (≤20 m and ≤100 m, respectively), the rate of formation of carbonate apatite layer was maintained in comparison with the native glass alone, constituting a promising material for application as dental prosthetic devices.
Investigation of 58S bioactive glass tablets
Cumhuriyet Science Journal, 2020
In this study, bioactive glass powders were successfully synthesized by using the sol-gel process and bioactive glass powders were tabletted by direct dry pressing method. The morphology and surface properties of bioactive glass tablets were examined via field emission scanning electron microscope (FE-SEM) devices. X-ray diffraction (XRD) was utilized to evaluate the phases formed in the sol-gel bioactive glass tablets. Surface characterization of the tablets immersed in simulated body fluid (SBF) was carried out with XRD, FE-SEM, and Fourier transform infrared (FTIR). XRD, FTIR, and EDS analysis proved that the sample contained hydroxyapatite. Also, the in vitro mineralization assay demonstrated that bioactive glass tablets are capable of inducing the creation of hydroxyapatite after dipped in SBF. All analyze results showed that bioactive glass tablets have good apatite-forming activity.
Dental Materials, 2019
Objective. The recently developed bioactive glass PC-XG3, which is suitable to coat zirconia implant surfaces with high adhesion strength may reduce the time of osseointegration and the marginal bone loss following implantation. The glass composition has been previously evaluated for cytotoxicity on fibroblast cells, and will now be used to evaluate the cell behavior of osteoblast cells. Methods. Three different surface morphologies were created with PC-XG3 on zirconia discs. A clinically tested zirconia implant surface as well as polished and machined zirconia served as a reference. Cell viability after 24 h, cell spreading after 30 min and 24 h and the respective morphology of human osteoblasts using scanning electron microscopy were evaluated. Additionally, the corrosive process of PC-XG3 in cell culture medium up to 7 d was measured. Results. Initial cell behavior of human osteoblasts was not accelerated by the PC-XG3 surface when compared to zirconia. Additionally, it was found that a decreased surface roughness promoted initial cell spreading. Storage in cell culture medium resulted in the accumulation of C and N on the bioglass surface while Mg, Si, K and Ca were decreased and crack formation was observed. Significance. Since initial spreading quality to a biomaterial is a crucial factor that will determine the subsequent cell function, proliferation, differentiation, and viability it can be assumed that a coating of zirconia implants with this bioactive glass will unlikely reduce osseointegration time.
Coatings on zirconia for medical applications
Biomaterials, 2000
In order to combine the mechanical properties of a high-strength inert ceramic (yttria-stabilised zirconia, ZrO }3%Y O , de"ned as zirconia in the text) with the speci"c properties of bioactive materials, some zirconia samples were coated by two bioactive phosphosilicate glasses and glass-ceramics: RKKP and AP40. Coatings of about 200}300 m thickness were prepared by a simple and low-cost "ring method. They were characterised by optical and scanning electron microscopy (SEM) and compositional analysis (EDS). The adhesion of the coatings on zirconia was tested by shear tests. Vickers indentations at the coating/zirconia interface were performed in order to observe the crack propagation path. The reactivity of glasses and glass-ceramics coatings towards a simulated body #uid (SBF), having the same ion concentration as that of human plasma, was evaluated and compared to that of the bulk glass and glass-ceramics, by examining the morphology of the reaction layer formed on the surface of the coated zirconia after one month of soaking in the SBF at 373C.
Zirconia (ZrO2) ceramic is widely used in dentistry as a clinical dental biomaterial. In this review, we are focusing on and summarizing the biological performance of zirconia under different surface characteristics. We have included an initial tissue cell attachment study on zirconia and bacterial adhesion on zirconia. Our results suggest that surface modifications applied on zirconia may change the interfacial surface characteristics e.g. surface roughness, surface free energy, and chemistry of zirconia. The modifications also result in advanced biological performance of zirconia, including enhanced tissue cell attachment and reduction of bacterial adhesion. The recent laboratory research has provided many interesting modification methods and showed clinically interesting and promising outcomes. A few of the outcomes are validated and have been applied in clinical dentistry.