Generic and disease-specific quality of life in adolescents with type 1 diabetes: comparison to age-matched healthy peers (original) (raw)
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Acta Paediatrica, 2007
O. Measuring self-reported, healthrelated, quality of life in adolescents with type 1 diabetes using both generic and disease-specific instruments. Acta Paediatr 2003; 92: 1190-1196 Aims: To describe perceived functional health and well-being and diabetes-related impact, worry and satisfaction with life in relation to demographic and clinical variables in a population of adolescents with type 1 diabetes. To compare perceived functional health and well-being between adolescents with diabetes and a group of healthy controls and to analyse the relationship between generic functional health and well-being and diabetes-related impact, worry and satisfaction with life. Methods: A total of 130 adolescents were invited to complete the Child Health Questionnaire (CHQ-CF87) and the Diabetes Quality of Life (DQOL) questionnaire modified for youths. A total of 115 (88.5%) subjects participated in the study; mean age 14.5 y (SD 1.86), mean duration of diabetes 6.99 y (SD 3.77, range 1-16 y), mean HbA 1c 9.3% (SD 1.62, range 6.2-14.0%). Fortyeight percent of the subjects were girls. Results: When compared with healthy adolescents, subjects with diabetes reported a significantly lower degree of general health. The CHQ-CF87 scales showed that higher age in adolescents with diabetes was associated with lower scores for mental health (p < 0.001), self-esteem (p < 0.001), behaviour (p = 0.004) and general health (p < 0.001). Findings from the DQOL questionnaire showed that older adolescents were more worried (p < 0.001), perceived a greater impact of diabetes on daily life (p = 0.008) and lower diabetes-related life satisfaction (p < 0.001). The scores for girls were lower than those for boys in assessment of mental health (p < 0.001), self-esteem (p = 0.004) and family cohesion (p = 0.002). Girls also reported a greater impact of diabetes (p = 0.028), more worries (p = 0.001) and less satisfaction with life (p = 0.006) than boys. Neither HbA 1c nor other clinical variables could sufficiently explain the variations in DQOL or CHQ-CF87.
Dovepress, 2022
Background: Type 1 diabetes mellitus (T1DM) is one of the most common chronic diseases during childhood and adolescence. It threatens the health and endangers life with consequences for the physical and emotional development of the child and adolescent. Our study aimed at determining the health-related quality-of-life (HRQoL) and factors affecting it in children and adolescents with T1DM. Methods: A hospital-based cross-sectional study was conducted among 379 randomly selected children and adolescents, 5-18 years of age, with T1DM on follow-up at endocrine clinics from 25 August to 25 September 2021. PedsQLTM 4.0 generic core scales were used to collect the data. Paired sample t-test was used to compare children's and adolescents' self-reports and caregiver's reports. Bivariable and multivariable linear regression is used to explore to identify significant predictor factors of HRQoL. Results: Total mean score of HRQoL was 88.42±10.82 as reported by the children and adolescents and 82.17±12.65 reported by their primary caregivers. According to self-reports, age (β=−0.197, p=0.028), mothers' educational status (β=0.242, p<0.001), fathers' educational status (β=0.259, p<0.001), fathers' occupation (β=0.170, p=0.038), frequency of insulin administration (β=−0.132, p=0.007), diabetes duration (β=−0.101, p=0.050), and frequency of monitoring of blood glucose (β=0.165, p=0.006) were statistically significant predictors of HRQoL, explaining 21.6% of the variability of total HRQoL scores of children and adolescents (R 2 =0.216, F (21,357)=5.968, p<0.001). Conclusion: Children and adolescents with T1DM in Ethiopia have relatively good HRQoL. Increased age, longer diabetes duration, and insulin administrations of three times per day were associated with decreased HRQoL scores. Educated parents, having an employed father, and frequent blood glucose monitoring were associated with higher HRQoL scores.
Journal of Child Health Care, 2013
This study aimed to investigate the association of the anthropometric, clinical variables and maximal oxygen uptake (VO2max) with diabetes-specific health-related quality of life (HRQoL) in youths with type 1 diabetes mellitus (T1DM) and to find the predictors of HRQoL and blood glucose control. A total of 239 youths with diabetes (124 boys and 115 girls) were recruited from diabetes-based summer camps. HRQoL assessment was carried out with the Pediatric Quality of Life Inventory™ 3.0 Diabetes Module (Information Resources Centre, Mapi Research Trust, France); VO2max was evaluated by conducting the 20-m shuttle run test. Higher VO2max and the insulin pump therapy were significant predictors of the HRQoL in the multiple regression analysis; other clinical and anthropometric variables had no effect. The better blood glucose control was explained only by the higher VO 2max . The good cardiorespiratory fitness (expressed by VO 2max ) has clinical and QoL benefits for paediatric patients with T1DM.
Diabetes care, 2017
Our objective was to characterize diabetes-specific health-related quality of life (D-HRQOL) in a global sample of youth and young adults with type 1 diabetes (T1D) and to identify the main factors associated with quality of life. The TEENs study was an international, cross-sectional study of youth, 8-25 years of age, with T1D. Participants (N = 5,887) were seen in clinical sites in 20 countries across 5 continents enrolled for 3 predetermined age groups: 8-12, 13-18, and 19-25 years of age. To assess D-HRQOL, participants completed the PedsQL Diabetes module 3.0 and were interviewed about family-related factors. Specifics about treatment regimen and self-management behaviors were collected from medical records. Across all age groups, females reported significantly lower D-HRQOL than did males. The 19-25-year age group reported the lowest D-HRQOL. Multivariate linear regression analyses revealed that D-HRQOL was significantly related to HbA1c; the lower the HbA1c, the better the D-H...
Health-Related Quality of Life of Youths with Type 1 Diabetes
2012
In the routine care of diabetes, mostly the clinical parameters are controlled and little attention is paid to the quality of life assessment. A questionnaire must be culturally adapted in the country where it is intended to be used. The aim of the study was to assess health-related quality of life in youths with type 1 diabetes using the PedsQL 3.0 Diabetes Module and to evaluate the psychometric properties in patient and control subjects.
Research Square (Research Square), 2022
Background: Living with type-I diabetes mellitus (T1DM) presents children and adolescents with various daily challenges associated with disease management, including signi cant lifestyle changes due to intensive therapeutic exogenous insulin regimes, the need for dietary restrictions, regular exercise, and frequent biochemical marker monitoring. This study aimed at determining diabetes related quality of life (DRQoL) and factors in uencing quality of life in Indian children and adolescents with T1DM. Methods: Three hundred seventy-nine randomly selected children and adolescents with T1DM were assessed using Pediatric quality of life inventory 3.2 diabetes module. Mean scores of DRQoL according to sociodemographic factors, and clinical variables were assessed by an independent sample t test, or ANOVA according to the characteristics of analyzed variables. Paired sample t-test was used to compare children's and adolescents' self-report with caregivers' report. Multivariable linear regression was used to identify the signi cant predictors of DRQoL. Result: The total score of the PedsQL Diabetes Module self-report were found to be 83.77±11.11 for the 5-12 years old and 80.27±13.52 for the 13-18 years old. Patients who attended education (β =-0.134, p= 0.013) and mothers of the patients being educated (β=0.300, p<0.001), and having insulin injection by primary care givers (β = 0.136, p=0.050) were positive determinants of DRQoL; while not attending diabetic education (β =-0.129, p=0.014) and an increase in the mean fasting blood sugar (FBS) (β =-0.130, p=0.016) were found to be negative determinants that explain 20.3% of the variability of total DRQoL scores of children and adolescents (R 2 =0.203, F(20,312)= 5.225, p<0.001). Conclusions: the quality-of-life score for children and adolescents with T1DM in Ethiopia was not su ciently good. The educational status of patients, mothers' educational status, fathers' occupation, type of individual administering insulin medication, attending diabetes health education and mean fasting blood sugar were found to be determinants of DRQoL.
Medical review, 2020
Introduction. Diabetes mellitus is a chronic disease that affects all aspects of life of pediatric patients, especially the psychological aspect, and hence the health-related quality of life. The aim of the study was to evaluate the effects of sociodemographic and clinical factors of pediatric patients with type 1 diabetes mellitus on self-assessment of health-related quality of life. Material and Methods. The research was conducted as a cross-sectional study. The sample included 37 pediatric patients aged 8 to 18 years, who were diagnosed with the type 1 diabetes mellitus six months or longer before enrollment into the study. The research instruments used in the study were the Serbian version of child-friendly EuroQol-5D-Y youth questionnaire and medical history data (gender, age, time since diagnosis - in years, glycosylated hemoglobin values, type of insulin therapy). Results. The total score of general health on the visual analogue scale was 80.54 on average (standard deviation ...
General Quality of Life in Youth With Type 1 Diabetes
Diabetes Care, 2003
OBJECTIVE—To evaluate self-report and parent proxy report of child/teen general quality of life in youth with type 1 diabetes, compare their responses with those of a general pediatric population, and identify relationships between diabetes management, diabetes-related family behavior, and diabetes-specific family conflict with quality of life in youth with type 1 diabetes. RESEARCH DESIGN AND METHODS—Study participants included 100 children, 8–17 years of age (12.1 ± 2.3), with type 1 diabetes for 0.5–6 years (2.7 ± 1.6). Each child and a parent completed the Pediatric Quality of Life Inventory (PedsQL), completed the Diabetes Family Conflict Scale, and provided data on parent involvement in diabetes management. An independent measure of adherence to treatment assessed by the patient’s clinician and a measure of glycemic control (HbA1c) were also collected. RESULTS—PedsQL responses from youth with type 1 diabetes were stable over 1 year and similar to norms from a healthy standardi...