Fruit Flavonoids of Some Species of Subgenera Esula and Chamaesyce (Euphorbia) in Iran (original) (raw)

Flavonoids of 17 species of Euphorbia (Euphorbiaceae) in Iran

Toxicological & Environmental Chemistry, 2009

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Study on Flavonoids and Triterpenoids Content of some Euphorbiaceae Plants

The Spurge family (Euphorbiaceae) is a large family of flowering plants. Two plant species of this family were collected from the Egyptian desert, extracted with methanol subjected to silica gel column chromatography to give six compounds, three compounds from each plant. The compounds isolated from the methanol extract of Euphorbia retusa Forssk were identified as kaempferol-3-beta-D glucopyranosyl (1), 3-O-alpha-L-xylopyranosyl (1→3)-alpha-L xylopyranosyl (1→2), beta-D glucopyranosyl-lup1,12-diene-3,21-diol (2) and 5,7,8,3',4'-pentahydroxy-3-methoxyflavone (3) and the compounds isolated from Euphorbia paralais L. identified as 3,5,3'-trihydroxy-6,7-d-methoxy-4' (7"-hydroxygeranyl-1"-ether) flavones (4), 3-O-syringic acid (1→4)-alpha-L-xylopyranosyl (1→3), beta-D-rahminopyranosyl hederagenin (5) and 3-O-syringic acid (1→4), beta-D-rahminopyranosyl (1→3),beta-D-rahminopyranosyl hederagenin (6). The structure of the isolated compounds was elucidated by chemi...

Phytochemical investigation And high performance thin layer chromatography (HPTLC) identification of flavonoids and phenolic acids in Euphorbia cyathophora (Family: Euphorbiaceae) cultivated in Iraq

Annals of Tropical Medicine and Public Health, 2020

The objective of the current work was to investigate the phytochemicals, and to determine the types of phenolic acids and flavonoids in aerial parts of Euphorbia cyathophora since no previous work has been done in Iraq. The aerial parts of Euphobiacyathophorawere defatted by petroleum ether 40-60˚C, then extracted by 80% ethanol using soxhelt apparatus. The hydroalcoholic extract was subjected to preliminary phytochemical analysis. Then Fractionation using chloroform, ethyl acetate, and n. butanol. The ethyl acetate and n. butanol fractions were separately reflexed with 5% HCl for several hours. Fractions (ethyl acetate and n. butanol) before and after hydrolysis were examined by HPTLC (high performance thin-layer chromatography) for their flavonoids and phenolic acids contents. Anthraquinon, cardiac glycosides, alkaloid and steroids were not detected in crude extract. Flavonoids and phenolic acids were detected in analyzed fractions. Quercetrin and rutin respectively were the main identified flavonoids in ethyl acetate and n. butanol fractions before hydrolysis; quercetin was the main detected aglycone in acidic hydrolyzed fractions. Chlorogenic acid and caffeic acid only detected in n. butanol fractions.

Total phenolics and flavonoids content, antioxidant activity and GC/MS analyses of Euphorbia grandialata

Journal of Applied Pharmaceutical Science

This study has been designed to study phenolic and flavonoid contents quantitatively; screen antioxidant activity and investigate unsaponifiable and saponifiable matters of Euphorbia grandialata R. aerial parts. Methods: The phenolics and flavonoids content were assayed by Folin-Ciocalteu reagent and aluminium chloride reagent respectively, while the anti-oxidant activity was done by 2, 2-diphenyl-1-picrylhydrazyl (DPPH).GC/MS analysis was used to analyze unsaponifiable and saponifiable matters. Results: Total phenolics result was calculated as (17.61 ± 1.2 μg gallic acid/g), total flavonoids as (4.495 ± 0.39 μg rutin/g) and anti-oxidants activity as (140.6 % μg ascorbic acid/g). The identified compounds in unsaponifiable matter were hydrocarbons (51.1 %), steroids and triterpenes (35.92%). The saponifiable matter showed fourteen components from which six were identified as methyl esters of saturated fatty acids (46.26%) and eight as methyl esters of unsaturated fatty acids (53.74 %). Conclusion: Euphorbia grandialata could be considered as a valuable source of natural antioxidants. This is the first report for phenolics and flavonoids content, antioxidant activity and GC/MS analysis of this plant.

Isolation of flavonols from Euphorbia wallichii by preparative High Performance Liquid Chromatography

2009

Flavonoids are a diverse group of natural products found in all plants. In present study three flavonols namely quercetin, kaemferol and myricetin were identified and isolated in Euphorbia wallichii in different solvents. Study was carried out on acid hydrolyzed methanolic extracts which was further fractionated into diethyl ether, n-butanol, ethyl acetate and water extracts. Quercetin was found to be the most abundant flavonol present in Euphorbia wallichii. [Nature and Science. 2009;7(8):86-88]. (ISSN 1545-0740).

Flavonoids from the Genus Euphorbia: Isolation, Structure, Pharmacological Activities and Structure–Activity Relationships

Pharmaceuticals

Plants of the genus Euphorbia are widely distributed across temperate, tropical and subtropical regions of South America, Asia and Africa with established Ayurvedic, Chinese and Malay ethnomedical records. The present review reports the isolation, occurrence, phytochemistry, biological properties, therapeutic potential and structure–activity relationship of Euphorbia flavonoids for the period covering 2000–2020, while identifying potential areas for future studies aimed at development of new therapeutic agents from these plants. The findings suggest that the extracts and isolated flavonoids possess anticancer, antiproliferative, antimalarial, antibacterial, anti-venom, anti-inflammatory, anti-hepatitis and antioxidant properties and have different mechanisms of action against cancer cells. Of the investigated species, over 80 different types of flavonoids have been isolated to date. Most of the isolated flavonoids were flavonols and comprised simple O-substitution patterns, C-methyl...

Investigation of Phytochemical in Euphorbia heterophylla and Euphorbia rothiana

The genus Euphorbia attracted the attention of many researchers as it is poorly studied. Euphorbia heterophyla and Euphorbia rothiana were selected and aimed to investigate the presence of phytochemicals screenings in leaf and stem. Aqueous, Acetone and Methanol Solvents were used for phytochemical analysis. The phytochemical analysis reveals the presence of phenolic compound in leaf and stem of the plants in all extracts and flavonoid using aqueous and methanol extracts. Our findings provides evidence, that aqueous and organic solvent extracts of these plants contain medicinally important bioactive compounds.

HPLC analysis of flavonoids in Eupatorium littorale

Journal of the Brazilian Chemical Society, 2001

Neste trabalho são descritos o isolamento e a identificação de eupafolina e hispidulina das folhas secas de Eupatorium littorale (Asteraceae). Foi desenvolvido também um método para a detecção desses flavonóides e de rutina na planta, utilizando a técnica de CLAE em fase reversa com detetor de arranjo de fotodiodos. Eupafolina e hispidulina foram quantificados sendo encontradas as concentrações de 0,29% e 0,21%, respectivamente.