Quality assurance in proton beam therapy using a plastic scintillator and a commercially available digital camera (original) (raw)
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Australasian Radiology, 2008
The International Commission on Radiation Units (ICRU) is concerned with the development of internationally acceptable recommendations regarding the quantities and units of radiation and radioactivity, measurement and application procedures, and the physical data needed for these procedures. Chaired by Andre Wambersie, the ICRU now presents Report 59, which specifically addresses the rationale for and the history of proton therapy. This report covers the production of proton beams for therapy, relevant quantities and units, proton interactions with matter, proton absorbed dose and beam monitoring and relative dosimetry. The report concludes with recommendations for the determination of absorbed dose in a phantom. A useful quality assurance example and a dosimetry worksheet are included in the Appendices. Some eight pages of references and tables of proton-stopping powers and ranges from 0.1 MeV to 300 MeV for a wide range of materials undoubtedly completes this important resource for proton therapy.
The Indiana University proton radiation therapy project
Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 1993
A fixed horizontal beam line at the Indiana University cyclotron facility (IUCF) has been equipped for proton radiation therapy treatment of head, neck, and brain tumors. The complete system will be commissioned and ready to treat patients early in 1993. IUCF can produce external proton beams from 45 to 200 MeV in energy, which corresponds to a maximum range in water of 26 cm. Beam currents over 100 nA are easily attained, allowing dose rates in excess of 200 cGy/min, even for large fields. Beam spreading systems have been tested which provide uniform fields up to 20 cm in diameter. Range modulation is accomplished with a rotating acrylic device, which provides uniform depth dose distributions from 3 to 18 cm in extent. Tests have been conducted on detectors which monitor the beam position and current, and the dose symmetry. This report discusses those devices, as well as the cyclotron characteristics, measured beam properties, safety interlocks, computerized dose delivery/monitoring system, and future plans.
Proton Therapy Dose Characterization and Verification
2013
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Towards effective and efficient patient-specific quality assurance for spot scanning proton therapy
Cancers, 2015
An intensity-modulated proton therapy (IMPT) patient-specific quality assurance (PSQA) program based on measurement alone can be very time consuming due to the highly modulated dose distributions of IMPT fields. Incorporating independent dose calculation and treatment log file analysis could reduce the time required for measurements. In this article, we summarize our effort to develop an efficient and effective PSQA program that consists of three components: measurements, independent dose calculation, and analysis of patient-specific treatment delivery log files. Measurements included two-dimensional (2D) measurements using an ionization chamber array detector for each field delivered at the planned gantry angles with the electronic medical record (EMR) system in the QA mode and the accelerator control system (ACS) in the treatment mode, and additional measurements at depths for each field with the ACS in physics mode and without the EMR system. Dose distributions for each field in ...
Operation of the TRIUMF Proton Therapy Facility
Proceedings of the 1997 Particle Accelerator Conference (Cat. No.97CH36167), 1998
The Proton Therapy Facility at TRIUMF is now in routine operation treating ocular tumours using 70 MeV protons extracted from the 500 MeV H , cyclotron. This paper describes the proton beam line, treatment control and dosimetry systems which are designed to provide accurate treatment dose delivery. The reproducibility of the shape and range of the unmodulated Bragg peak for various operating conditions of the cyclotron is discussed along with the technique for producing a uniform modulated or spreadout Bragg peak. The patient positioning chair, which has six motorized degrees of freedom, the patient mask and bite-block, and the X-ray verification system ensure submillimeter positioning accuracy. Patient treatments are scheduled one week per month with the treatment dose of 50 proton-Gy delivered in four daily fractions.
Technical Note: A prototype clinical proton radiography system
arXiv: Medical Physics, 2020
Purpose: To demonstrate a proton imaging system based on well-established fast scintillator technology to achieve high performance with low cost and complexity, with the potential of a straightforward translation into clinical use. Methods: The system tracks individual protons through one (X, Y) scintillating fiber tracker plane upstream and downstream of the object and into a 13 cm-thick scintillating block residual energy detector. The fibers in the tracker planes are multiplexed into silicon photomultipliers (SiPMs) to reduce the number of electronics channels. The light signal from the residual energy detector is collected by 16 photomultiplier tubes (PMTs). Only four signals from the PMTs are output from each event, which allows for fast signal readout. A robust calibration method of the PMT signal to residual energy has been developed to obtain accurate proton images. The development of patient-specific scan patterns using multiple input energies allows for an image to be prod...
A prototype proton radiography system for clinical use
arXiv: Medical Physics, 2020
Verification of patient specific proton stopping powers obtained in the patient treatment position can be used to reduce the distal margins needed in particle beam planning. Proton radiography can be used as a pre-treatment instrument to verify integrated stopping power consistency with the treatment planning CT. Although a proton radiograph is a pixel by pixel representation of integrated stopping powers, the image may also be of high enough quality and contrast to be used for patient alignment. This investigation qualifies the accuracy and image quality of a prototype proton radiography system on a clinical proton delivery system. We have developed a clinical prototype proton radiography system designed for integration into efficient clinical workflows. We tested the images obtained by this system for water-equivalent thickness (WET) accuracy, image noise, and spatial resolution. We evaluated the WET accuracy by comparing the average WET and rms error in several regions of interes...
Proton radiography and tomography with application to proton therapy
The British Journal of Radiology, 2015
An internationally renowned expert in image engineering based at the University of Lincoln has developed new medical imaging technology that could revolutionise cancer treatment. A consortium, led by Distinguished Professor of Image Engineering Nigel Allinson, created DynAMITe, the world's largest radiationtolerant silicon imager-200 times larger
Project of the demonstration center of proton therapy at DLNP JINR
Physics of Particles and Nuclei Letters, 2015
JINR is one of the leading research centers of proton therapy in Russia. The modern technique of 3D conformal proton radiotherapy was first effectuated in Russia in this center, and now it is effectively used in regular treatment sessions. A special Medial Technical Complex (MTC) was created at JINR on the basis of a phasotron used for proton treatment. About 100 patients undergo a course of fractionated treatment here every year. Over the last 14 years since the startup of the Dubna radiological department, more than 1000 patients have been treated by protons. The project of the demonstration center of proton therapy is pro posed on the basis of a superconducting 230 MeV synchrocyclotron S2C2 of new IBA compact proton system Proteus ONE. The superconducting synchrocyclotron is planned to for instillation instead of a phasotron in the Medical Technical Complex, DLNP. For the demonstration center, a new transport line will be designed for beam delivery to the medical cabin.