Comparative Study of Ropivacaine with Dexmedetomidine 1µg/Kg and Ropivacaine with Clonidine 1µg/Kg by Epidural Route in Patients Undergoing Lower Abdominal and Lower Limb Surgeries Comparative Study of Ropivacaine with Dexmedetomidine 1µg/Kg and Ropivacaine with (original) (raw)
INTRODUCTION: Regional anaesthesia is safe, cost-effective approach wherever feasible and also it is the technique of choice for providing excellent postoperative analgesia. Spinal anaesthesia, regional anaesthetic technique, the early-onset and sure success of the method, ease in technique but duration of anaesthesia and analgesia is limited. Epidural anaesthesia, has many advantages for a prolonged duration with frequent top-ups for delivering excellent postoperative analgesia. It contributes to intraoperative hemodynamic stability reduce perioperative stress response, decrease in complications and improving patient outcome by relieving postoperative pain, decreases the incidence of thromboembolic events. AIMS AND OBJECTIVES OF THE STUDY: To evaluate the efficacy of dexmedetomidine and clonidine, adjuvant to ropivacaine in epidural anaesthesia for lower abdominal and lower limb surgeries. Compare Onset and duration of sensory blockade, motor blockade, duration of analgesia, haemodynamic changes and side effects. MATERIALS AND METHODS: 60 patients aged between 18 and 60 belonging to ASA I and II divided into two groups, each group consist of 30 patients. Group RC: Receives 15ml of 0.75 % ropivacaine with 1 µg/kg clonidine. Group RD: Receives 15ml of 0.75 % ropivacaine with 1 µg/kg dexmedetomidine. Injected epidurally undergoing lower abdominal and lower limb surgeries. All patients are managed similarly and the effect of onset, duration of sensory, motor blockade, haemodynamic and complications are evaluated. Results obtained were tabulated and analysed. RESULTS: The onset and duration of sensory blockade were faster in group RD than group RC which was statistically significant. The onset and duration of Motor blockade is more intense and Sedation score is greater in RD group than RC group which is highly significant. Side effects are more with RD group than RC which are treatable. CONCLUSION: The addition of Dexmedetomidine to Ropivacaine for epidurally to shorten the onset of block and prolong the duration of block. The dosage of 1µg/kg used in the study significantly increase the duration of the analgesia.
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