149 Diagnosis of Osteoarthrhis by Quantification of Tibia Trabecular Bone Structure from Magnetic Resonance Imaging (original) (raw)

Poster Presentations / Osteoarthritis and Cartilage 19S1 (2011) S53-S236 S75 of CCL3 and CCL4 were over 21 ng/L in normal adults, which were much higher than IL-6 and IL-1b ( ). The concentration of CCL3 was 36.34±2.68 ng/l, 55.30±4.05 ng/l, and 62.56±2.39 ng/l in normal adults, medial OA patients, and severe OA patients ( ). The ratio of CCL4 was significant different in normal adults and different stages of OA patients , and the concentration was 21.75±4.80 ng/l, 43.80±4.27 ng/l, and 60.50±5.87 ng/l ( ). Conclusion: CCL3, CCL4, CXCL2, IL-8 and IL-1b could be serum biomarkers to identify healthy adults, early stage OA patients and late stage OA patients from our primary data, especially CCL4 and CXCL2 were detectable and useful.