Mass Spectrometry: A Guide For The Clinician (original) (raw)

Metabolic profiling using mass spectrometry (MS) has become a crucial tool in clinical research for understanding complex biological systems. This review outlines the fundamentals of MS, the distinction between targeted and untargeted metabolic profiling approaches, and the role of metabolomics in biomarker discovery relevant to diseases such as cancer, diabetes, and hypertension. The integration of various spectroscopic techniques and statistical methods facilitates the identification of metabolites in biofluids and tissues, enhancing disease diagnosis and personalized medicine.