Efficient and Practical Synthesis of ( R )-2-Methylpyrrolidine (original) (raw)

The Journal of Organic Chemistry, 2006

Abstract

An efficient, practical, and high yielding synthesis of (R)-2-methylpyrrolidine is described. The sequence allows for the scalable preparation of the target compound in just four synthetic steps and proceeds in 83% overall yield and >99% optical purity from readily available starting materials.

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