Early Life Stage Toxicity of 2,3,7,8-Tetrachlorodibenzo- p-dioxin in Zebrafish ( Danio rerio (original) (raw)

1997, Toxicology and Applied Pharmacology

siveness to TCDD early life stage toxicity coupled with the consid-Early Life Stage Toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin erable information on developmental biology and genetics of zebrain Zebrafish (Danio rerio). HENRY, T. R., SPITSBERGEN, J. M., fish provides a foundation for future investigations into the HORNUNG, M. W., ABNET, C. C., AND PETERSON, R. E. (1997). mechanism of TCDD developmental toxicity. ᭧ 1997 Academic Press Toxicol. Appl. Pharmacol. 142, 56-68. Toxicity and histopathology of 2,3,7,8-tetrachlorodibenzo-p-di-Polychlorinated dibenzo-p-dioxins (PCDDs), dibenzooxin (TCDD) in zebrafish (Danio rerio) early life stages was charfurans (PCDFs), and biphenyls (PCBs) comprise a family acterized from 12 to 240 hr postfertilization (hpf) following waterof bioaccumulative halogenated aromatic hydrocarbons borne exposure of newly fertilized eggs. TCDD did not increase which resist degradation and persist in the environment, egg mortality (0-48 hpf), nor did it affect time to hatching (48posing a potential risk to fish, wildlife, and human health.