Fabrication of biosensors by attachment of biological macromolecules to electropolymerized conducting films (original) (raw)

The integration of biological macromolecules with electrochemical devices has led to the development of biosensors, which are critical for analyzing target analytes across various fields. Central to the advancement of these biosensors is the challenge of effectively immobilizing biomolecules onto conductive surfaces while preserving their functional properties. Electropolymerized conductive films present a promising method for this immobilization, allowing for a precise and robust method of entrapment that benefits from electrochemical deposition techniques. This paper reviews the strategies for incorporating biomolecules, particularly enzymes, into conducting polymer matrices such as polypyrrole, highlighting both the mechanisms of interaction and the potential applications in biosensing.