MUR-Full Article-10.1007 s11096-014-9962-5 (original) (raw)

31.04.15 Int J Pharm Bio Sci 2015 April 6(2)(B)1318-1326.pdf

The "International Journal of Pharma and Bio Sciences" (IJPBS) is an international journal in English published quarterly. The aim of IJPBS is to publish peer reviewed research and review articles rapidly without delay in the developing field of pharmaceutical and biological sciences www.ijpbs.net Indexed in Elsevier Bibliographic Database (Scopus and EMBASE) SCImago Journal Rank 0.288 Impact factor 2.958* Elsevier Chemical Abstracts Service (www.cas.org) SNIP value -0.77 SJR -0.288 IPP -0.479

World Journal of Pharmaceutical Sciences

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Acknowledgement to authors reviewers and editors of journal of pharmacy and pharmacology

Marco Milanese, Mohd Hezmee Mohd Noor, Naj Sharif, Yildirim Sara, Glenn Marsboom, Yu Chiao Yang, Jinyong Peng, Muhammad Shahzad, Dalia Osama, Hazem M Shaheen, Ashraf Ahmed Elghoneimy, Aarthi Manoharan, Olga Tovchiga, C. Ganesh Kumar, Praveen T.K, Ashok Kumar Datusalia, Irwin Rose Alencar Menezes, Julian Albarran Juarez, Magdalena Pietka, Ayse Gelal, Young Ho Seo, Giambattista Bonanno, Miguel Lopez Lazaro, Xiangchun Shen, Maliheh Ghadiri, Arun Kumar Jaiswal, Maria Ayub, Christian Caroli, Yousef Alomi, Belayneh Kefale Gelaw, C. Jayachandran, Mohammed Abdalla Hussein, Jenny Jeehan Nasr, Ehab Said Ibrahim EL Desoky, Sameh Saad Zaghlool Ahmed, Giulio Tarro, Guldem Mercanoglu, Sakir Ozgur Keskek, Durisova Maria, Godofreda V Dalmacion, Carlota Saldanha, Ralph Santos-Oliveira, Saganuwan, Yusuf Tutar, GUO Rui-chen, Ayesha Ahmed, Jan Olof Karlsson.

PHARMACEUTICAL SCIENCES Research Article RECEIVED ON 05-12-2011 ACCEPTED ON 02-01-2012

2014

Polyherbal drug formulations having hepatoprotective activity is the widely recognized and utilized therapy in the management of various liver dysfunctions. To evaluate efficacy and tolerability of Trisoliv ® Syrup in the management of various liver dysfunctions. Open, non-comparative, multi-centre, post marketing study. 50 patients suffering from various liver dysfunction like were enrolled in this study, 46 patients completed the study. Patients were given hepatoprotective syrup containing Andrographolides + Sorbitol + Tricholine citrate (A + S + T) 10 ml 2 to 3 times in a day for 8 weeks. The subjective clinical improvement in (jaundice symptoms, fatigue, and loss of appetite) was assessed on a predefined 0 to 3 score scale. Total bilirubins (TB), SGOT / AST, SGPT/ALT, serum alkaline phosphatase were assessed at baseline and end of 8 weeks. Secondary outcomes were patient’s assessment about efficacy and tolerability of the hepatoprotective product Trisoliv. After 8 weeks of Triso...

Pharmaceutical Sciences Review Article Received on 26-10-2011 Accepted on 26-11-2011

2014

Nanomedicine is an innovative and highly applicable tool in cancer.Nanomedicine is engineered nano scale 1-100nm structures and devices for diagnosis and therapy for cancer.Recently nanodevices capable of detecting cancer at its earliest stages, pinpointing it’s location within the body and delivering anticancer drugs specifically to malignant cells.Nanotechnology is expected to have a dramatic impact on medicine. The application of nanotechnology for treatment, diagnosis, monitoring, and control of biological systems is now often referred to as nanomedicine. Nanotubes, nanoshels, nanowires are different types of devices applicable in cancer diagnosis.The ultimate goal of nanomedicine is to develop well engineered nanotools for the prevention, diagnosis and treatment of many diseases. The extraordinary growth in nanotechnology has brought us closer to be able to vividly visualize molecular and cellular structures. This technology has ability to differentiate between normal and cance...

Vol. 2, Issue 12, December 2014, PharmaTutor, Paper-4.pdf

Solubility is one of the essential parameters to achieve bioavailability of drug in systemic circulation to produce expected therapeutic response. Nearly 40% of new drug molecules face solubility challenge. Though several techniques like micronization, crystal engineering, hydrotrophy, solid dispersion and so forth were available for solubility enhancement of poorly soluble drugs based on physical and chemical modification, prodrug approach is a vital technique amongst the other. Prodrugs are biologically inactive compound which can be metabolized in the body to produce active drug. It is estimated that currently about 10% of all world-wide approved drugs are prodrugs. This review extensively confers the role of prodrugs and the kind of promoieties used for solubility enhancement.