Prevalence of Methicillin-resistant Staphylococcus aureus and Antibacterial Susceptibility among Patients with Skin and Soft Tissue Infection at Ibb City, Yemen (original) (raw)
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Lijec̆nic̆ki vjesnik, 2008
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Background: Methicillin resistant Staphylococcus aureus (MRSA) is an important nosocomial pathogen causing significant mortality and morbidity. It is associated with a wide spectrum of infections ranging from mild skin and soft tissue infections to life threatening sepsis. Infected and colonized patients are the main reservoirs of infection and hand carriage by health care workers is the predominant mode of transmission. Aim: This study was undertaken to determine the prevalence of MRSA and their susceptibility pattern at SSG hospital, Baroda. Materials and Methods: 150 isolates of Staphylococcus aureus were obtained from different clinical specimens from hospitalized patients. They were screened for methicillin resistance by standard laboratory procedures. Susceptibility to beta lactams, aminoglycosides, macrolides, fluoroquinolones, glycopeptides and Oxazolidinones were determined by disc diffusion method. Results: Among the 150 Staphylococcus aureus isolates studied, 65 (43.3%) were MRSA. Among the 65 MRSA isolates are 96.93% susceptible to Vancomycin, 100% susceptible to Linezolid and 35.39% susceptible to Gentamicin, 12.31% susceptible to Azithromycin; 32.31% susceptible to Clindamycin and 00% susceptible to penicillin, oxacillin & cefoxitin. Conclusion: The MRSA isolates were associated with a high degree of co-resistance to other groups of antimicrobial agents. Active screening and compliance with recommended infection control practices play an important role in the control of MRSA.
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International journal of health sciences
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Methicillin Resistant Staphylococcus aureus MRSA in patients of CBMCH Mymensingh Bangladesh
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Title:-Prevalence of Methicillin Resistant Staphylococcus aureus (MRSA) in Hospitalized Patients
Abstract:- Methicillin resistant Staphylococcus aureus (MRSA) are important nosocomial pathogens. They spread easily in the hospital environment and present therapeutic problems, it is thus important to monitor their prevalence in the hospital. A total of 536 blood, pus and wound swabs from different clinical sites were processed. A total of 238 (44.40%) Staphylococcus aureus were isolated. Out of these 199 i.e. 37.12% were MRSA. Methicillin resistance was detected by oxacillin disc. A study of antibiogram showed that all strains were uniformly susceptible to vancomycin. The common places for isolation were Surgery (33.2%) followed by Orthopaedics(17.6%) and Skin (16.58%). MRSA were seen to be least prevalent in CCU, Gynaecology and NICU in our hospital. This may be due to constant sensitization of the hospital staff and implementation of infection control practices in these areas. Key Words:- MRSA