Localized Giant Cell Tenosynovial Tumor Seen in the Knee Joint (original) (raw)

Unusual Occurrence of Tenosynovial Giant Cell Tumor in Hoffa's Fat Pad: A Potential Differential Diagnosis for Nontraumatic Knee Swelling and Pain

Cureus, 2020

A tenosynovial giant cell tumor (TGCT) is a benign lesion whose presence in Hoffa's pad has rarely been reported. This unique case report discusses a 33-year-old female patient who presented with swelling and pain in her left knee. Clinical and MRI findings were used to make the diagnosis, which was confirmed on a histopathological basis. The patient had a large tumor (5 × 3 × 3 cm) in Hoffa's fat pad, which was diagnosed as TGCT and managed with open resection due to its size. At follow-up after 20 months, the patient was asymptomatic, and there was no local recurrence of the tumor.

Localised tenosynovial giant cell tumour of the infrapatellar fat pad mimicking an intra-articular loose body -A case report

Indian Journal of Orthopaedics Surgery, 2023

Tenosynovial giant cell tumour is a benign lesion which presence in the infrapatellar fat pad is uncommon. Herein, we report a unique case of a young female patient who presented with a loose body sensation at the knee. Surgery revealed a localized swelling in the infrapatellar fat pad which was treated with an open excisional biopsy of the mass. Diagnosis of giant cell tumour is confirmed by histopathological examination. Keywords: Giant cell tumour, Infrapatellar fat pad, Magnetic resonance imaging, Tenosynovial giant cell tumour

Monoarticular, Multifocal, Localized Tenosynovial Giant Cell Tumor of the Knee

JBJS case connector, 2020

Case: We present a 37-year-old man with uniarticular, multifocal, localized tenosynovial giant cell tumor (TSGCT) of the knee. He was treated with arthroscopic partial synovectomy of each tumor foci alone without the use of any adjuvants. At a 2-year follow-up, he had painless, full function of the knee with no signs of disease recurrence. Conclusion: There have been several reports of multiple joints or multiple compartments in and around a joint involved with TSGCT in the same patient, but this is the first case reported to our knowledge of multiple discrete foci within the same joint.

Surgical Treatment of Localized-Type Tenosynovial Giant Cell Tumors of Large Joints

Journal of Bone and Joint Surgery, 2019

Update This article was updated on April 9, 2020, because of a previous error. On page 1309, in the list of Tenosynovial Giant Cell Tumors (TGCT) Study Group members, the contributor name that had read “M. Wook Joo” should have read “M.W. Joo.” An erratum has been published: J Bone Joint Surg Am. 2020 May 20;102(10):e49. Background: Localized-type tenosynovial giant cell tumor (TGCT) is a rare, neoplastic disease with only limited data supporting treatment protocols. We describe treatment protocols and evaluate their oncological outcome, complications, and functional results in a large multicenter cohort of patients. A secondary study aim was to identify factors associated with local recurrence after surgical treatment. Methods: Patients with histologically proven localized TGCT of a large joint were included if they had been treated between 1990 and 2017 in 1 of 31 tertiary sarcoma centers. Of 941 patients with localized TGCT, 62% were female. The median age at initial treatment wa...

Tenosynovial giant cell tumor of cruciate ligament: A case report and review

International Journal of Surgery Case Reports, 2022

Introduction: Tenosynovial giant cell tumor (TSGCT) is a slow-growing soft tissue tumor that develops from the synovial tissue of tendon sheaths, joints, or bursae. In the knee, this type of tumor is uncommon. Giant cell tumors of the cruciate ligaments' tendon sheath are far more infrequent. Only 16 localized TSGCTs of the cruciate ligaments have been recorded in the literature to our knowledge, with 9 involving the anterior cruciate ligament (ACL) and 7 involving the posterior cruciate ligament (PCL). Case presentation: We present a rare case of localized TSGCT arising from the PCL's femoral insertion in a 44-yearold male, as well as a literature review on localized TSGCT of cruciate ligaments in the knee. The diagnosis of tumor's presence was made using MRI while the definitive diagnosis was obtained through intraoperative evaluation and postoperative pathology. Conclusion: Arthroscopic tumor resection was an effective and safe treatment option based on the available data.

Diffuse tenosynovial giant cell tumour of the temporomandibular joint

International Journal of Oral and Maxillofacial Surgery, 2012

Tenosynovial giant cell tumour (TGCT) is a rare benign proliferative disorder of the synovium characterised by destructive invasion by synovial-like mononuclear cells. Two variants have been distinguished: a localized (TGCT-L) and a diffuse (TGCT-D) type. TGCT usually affects adults with a peak incidence in the fifth and sixth decades of life and is more often seen in women than in men. One of the most common soft tissue tumours of the hand (finger joints and tendon sheaths), it is exceedingly uncommon in the head or neck. Only three cases of TGCT-D have been described in the literature. This report presents a case of TGCT-D in the temporomandibular joint.

Giant-cell tumor of the synovial membrane

Arthroscopy: The Journal of Arthroscopic & Related Surgery, 2000

Giant-cell tumor of the synovia is a benign neoplasm characterized histologically by proliferating histiocytes bearing lipids and hemosiderin intermingled with a variable number of multinuclear giant cells. Areas of predilection are the hand, and in the case of synovial joints, the knee joint is particularly affected. Clinically, patients have signs of mechanical derangement and, with the knee joint, meniscal symptoms and locking are often present. Joint effusion without previous trauma is another typical finding. Diagnosis is carried out by radiographic tools and has to be confirmed histologically. Giant-cell tumor of the synovia is treated by local excision either by arthroscopy or by arthrotomy. To our knowledge, the case we present is the largest giant-cell tumor of the synovia in the knee joint ever described in literature.