Effects of Aflatoxin B-1 and Fumonisin B-1 on Blood Biochemical Parameters in Broilers (original) (raw)

The individual and combined effects of dietary aflatoxin B 1 (AFB 1) and fumonisin B 1 (FB 1) on liver pathology, serum levels of aspartate amino-transferase (AST) and plasma total protein (TP) of broilers were evaluated from 8 to 41 days of age. Dietary treatments included a 3 × 3 factorial arrangement with three levels of AFB 1 (0, 50 and 200 μg AFB 1 /kg), and three levels of FB 1 (0, 50 and 200 mg FB 1 /kg). At 33 days post feeding, with the exception of birds fed 50 mg FB 1 only, concentrations of AST were higher (p < 0.05) in all other treatment groups when compared with controls. Plasma TP was lower (p < 0.05) at six days post feeding in groups fed 200 μg AFB 1 /kg alone or in combination with FB 1. At day 33 days post feeding, with the exception of birds fed the highest combination of AFB 1 and FB 1 which had higher plasma TP than control birds , plasma TP of birds fed other dietary treatments were similar to controls. Broilers receiving the highest levels of AFB 1 and FB 1 had bile duct proliferation and trabecular disorder in

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