Dynamic interaction of SARAF with STIM1 and Orai1 to modulate store-operated calcium entry (original) (raw)

SERAF, a Novel Regulator of Store Operated Calcium Entry

Adi Raveh

Biophysical Journal, 2012

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Orai1 and STIM Reconstitute Store-operated Calcium Channel Function

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Journal of Biological Chemistry, 2006

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Bidirectional regulation of calcium release–activated calcium (CRAC) channel by SARAF

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STIM1, an essential and conserved component of store-operated Ca2+ channel function

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SARAF Inactivates the Store Operated Calcium Entry Machinery to Prevent Excess Calcium Refilling

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The Calcium Store Sensor, STIM1, Reciprocally Controls Orai and CaV1.2 Channels

Youjun Wang

Science, 2010

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Functional interactions among Orai1, TRPCs, and STIM1 suggest a STIM-regulated heteromeric Orai/TRPC model for SOCE/lcrac channels

Lutz Birnbaumer

Proceedings of the National Academy of Sciences of the United States of America, 2008

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SARAF modulates TRPC1, but not TRPC6, channel function in a STIM1-independent manner

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The Biochemical journal, 2016

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Functional interactions among Orai1, TRPCs, and STIM1 suggest a STIM-regulated heteromeric Orai/TRPC model for SOCE/Icrac channels

Michael Zhu

Proceedings of The National Academy of Sciences, 2008

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Orai1 Mediates the Interaction between STIM1 and hTRPC1 and Regulates the Mode of Activation of hTRPC1-forming Ca2+ Channels

Isaac Jardin

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Native Store-operated Ca2+ Influx Requires the Channel Function of Orai1 and TRPC1

Weizhong Zeng

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STIM and Orai1 Variants in Store-Operated Calcium Entry

Tarik Smani

Frontiers in pharmacology, 2015

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Role of STIM and Orai proteins in the store-operated calcium signaling pathway

Donald Gill

Cell Calcium, 2007

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Dynamic Assembly of TRPC1-STIM1-Orai1 Ternary Complex Is Involved in Store-operated Calcium Influx: EVIDENCE FOR SIMILARITIES IN STORE-OPERATED AND CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL COMPONENTS

Brij Singh

Journal of Biological Chemistry, 2007

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STIM2 Is an Inhibitor of STIM1-Mediated Store-Operated Ca 2+ Entry

Maria Spassova

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Editorial: Molecular Components of Store-Operated Calcium Entry in Health and Disease

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STIM and Orai: the long-awaited constituents of store-operated calcium entry

Péter Várnai

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STIM1 phosphorylation at Y316 modulates its interaction with SARAF and the activation of SOCE and ICRAC

Irene Frischauf

Journal of Cell Science, 2019

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A role for Orai in TRPC-mediated Ca2+ entry suggests that a TRPC:Orai complex may mediate store and receptor operated Ca2+ entry

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Proceedings of the National Academy of Sciences, 2009

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ORAI Calcium Channels: Regulation, Function, Pharmacology, and Therapeutic Targets

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Two-pore channel 2 (TPC2) modulates store-operated Ca2+ entry

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Novel Modulators of STIM-ORAI Calcium Entry Pathway

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Emerging perspectives in store-operated Ca 2+ entry: Roles of Orai, Stim and TRP

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Genome-Wide RNAi Screen of Ca2+Ca^{2+}Ca2+ Influx Identifies Genes That Regulate Ca2+Ca^{2+}Ca2+ Release-Activated Ca2+Ca^{2+}Ca2+ Channel Activity

Ying Yu

Proceedings of The National Academy of Sciences, 2006

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A Novel Modulator of STIM2-Dependent Store-Operated Ca2+ Channel Activity

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STIM1 has a plasma membrane role in the activation of store-operated Ca2+ channels

Maria Spassova

Proceedings of the National Academy of Sciences, 2006

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Stimulation of Ca 2+ ‐channel Orai1/STIM1 by serum‐and glucocorticoid‐inducible kinase 1 (SGK1)

Meerim Nurbaeva

The FASEB Journal, 2011

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Complex role of STIM1 in the activation of store-independent Orai1/3 channels

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A STIM2 splice variant negatively regulates store-operated calcium entry

Barbara A Niemeyer, Dalia Alansary

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The KSR2-calcineurin complex regulates STIM1-ORAI1 dynamics and Store-Operated Calcium Entry (SOCE)

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Role of STIM1 in the surface expression of SARAF

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Channels (Austin, Tex.), 2016

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