Maternal inflammatory bowel disease during pregnancy is not a risk factor for long-term morbidity of the offspring (original) (raw)

To investigate whether offsprings of women suffering from inflammatory bowel disease (IBD) during their pregnancy are at an increased risk for long-term pediatric morbidity. In this population-based cohort study we investigated the incidence of long-term (up to the age of 18 years) hospitalizations due to cardiovascular, endocrine, neurological, hematological, respiratory, gastrointestinal, and urinary pediatric morbidities of offsprings to mothers affected by inflammatory bowel disease during their pregnancy. Deliveries occurred between the years 1991-2014 in a regional tertiary medical center. Newborns with congenital malformations as well as multiple pregnancies were excluded from the study. During the study period 255,352 deliveries met the inclusion criteria; 278 offsprings were born to mothers with inflammatory bowel disease. During the follow-up period, children born to mothers with inflammatory bowel disease did not have an increased risk for long-term (up to the age of 18 y...