Klein, P., Vaughan, R., Borleis, J. & Devreotes, P. The surface cyclic AMP receptor in Dictyostelium Levels of ligand-induced phosphorylation, solubilization, identification of primary transcript, and developmental regulation of expression. J. Biol. Chem. 262, 358-364 (original) (raw)

A monospecific polyclonal antiserum to the surface cAMP receptor of Dictyostelium was developed and characterized. Key findings include the identification of two receptor forms, R and D, which differ in their phosphorylation states, and the study of their expression patterns during development. The receptor's role in mediating cAMP-induced aggregation and signaling responses in Dictyostelium was examined, highlighting its importance in regulating cellular differentiation and adaptation processes.