Mutation analysis of the N-ras proto-oncogene in active and remission phase of human acute leukemias (original) (raw)

Relapse cell population differs from acute onset clone as shown by absence of the initially activated N-ras oncogene in a patient with acute myelomonocytic leukemia

Markus Fopp

Blood, 1988

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The pattern of mutational involvement of RAS genes in human hematologic malignancies determined by DNA amplification and direct sequencing

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Blood, 1990

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Analysis of N-ras gene mutations in acute myeloid leukemia by allele specific restriction analysis

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N-ras gene mutations in acute myeloid leukemia: Accurate detection by solid-phase minisequencing

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Detection of some genetic mutations in H-Ras gene in acute and chronic leukemia

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Analysis of RAS gene mutations in cytogenetically normal de novo acute myeloid leukemia patients reveals some novel alterations

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Concurrent mutations in two different ras genes in acute myelocytic leukemias

John Lyons

Nucleic Acids Research, 1987

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Quantitative determination of the ratio of mutated to normal ras genes in the blood of leukemia patients by allele-specific PCR

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Leukemia Research, 1994

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NRAS mutations in de novo acute leukemia: prevalence and clinical significance

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Indian journal of biochemistry & biophysics, 2014

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Rapid Detection of N-RAS Gene Common Mutations in Acute Myeloid Leukemia (AML) Using High Resolution Melting (HRM) Method

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Asian Pacific Journal of Cancer Prevention, 2022

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The prognosis and durable clearance of RAS mutations in patients with acute myeloid leukemia receiving induction chemotherapy

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n-ras and k-ras Mutations Among Some Iraqi Patients with Acute Lymphoblastic Leukemia

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Ras oncogene mutation in multiple myeloma

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K-ras mutations and N-ras mutations in childhood acute leukemias with or without mixed-lineage leukemia gene rearrangements

Der-cherng Liang

Cancer, 2006

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The prognosis and durable clearance of RAS mutations in patients with acute myeloid leukemia receiving induction chemotherapy

Jacob Glass

American Journal of Hematology, 2021

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Ras oncogene mutations are rare late stage events in chronic myelogenous leukemia

Jose Andres Trujillo

Blood, 1989

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Determination of Ras-GTP and Ras-GDP in patients with acute myelogenous leukemia (AML), myeloproliferative syndrome (MPS), juvenile myelomonocytic leukemia (JMML), acute lymphocytic leukemia (ALL), and malignant lymphoma: assessment of mutational and indirect activation

Tomasz Zemojtel

Annals of Hematology, 2009

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RAS mutation in acute myeloid leukemia is associated with distinct cytogenetic subgroups but does not influence outcome in patients younger than 60 years

Rosemary Gale

Blood, 2005

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N-ras mutations are associated with poor prognosis and increased risk of leukemia in myelodysplastic syndrome

Oscar Lazcano

Blood, 1993

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N-RAS mutations in T-cell acute lymphocytic leukaemia: analysis by direct sequencing detects a novel mutation

Martin Cline

British Journal of Haematology, 1989

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The prognostic impact of K-RAS mutations in adult acute myeloid leukemia patients treated with high-dose cytarabine

Nashwa al-Azizi, Heba Gawish

OncoTargets and Therapy, 2011

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Mutational landscape, clonal evolution patterns, and role of RAS mutations in relapsed acute lymphoblastic leukemia

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Proceedings of the National Academy of Sciences of the United States of America, 2016

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High-throughput sequencing screen reveals novel, transforming RAS mutations in myeloid leukemia patients

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Mutation of Genes Affecting the RAS Pathway Is Common in Childhood Acute Lymphoblastic Leukemia

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High incidence of N and K-Ras activating mutations in multiple myeloma and primary plasma cell leukemia at diagnosis

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Human Mutation, 2001

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Activation of Ha-ras in human chronic granulocytic and chronic myelomonocytic leukaemia

RA Padua

Leukemia Research, 1988

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