A clinical study of dermatoses in diabetes to establish its markers (original) (raw)
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Patterns of dermatological disorders among diabetics
2013
Diabetes Mellitus is a common metabolic disorder associated with significant dermatological alterations. This study was set out to demonstrate the pattern of the various dermatological disorders seen among diabetic population in Obafemi Awolowo University Teaching Hospitals Complex Ile Ife, a tertiary health care institution in south west Nigeria. Infective skin conditions appear to occur with greater frequency compared to the non-infective dermatoses and poor glycaemic control seems to be the most significant predictor of the presence of such skin lesions (p<0.001). Among diverse numbers of cutaneous lesions seen in this study, superficial fungal infections accounted for the highest prevalence and was seen in 35.4%. Pruritus ranked next with a prevalence of 16.7%. Others include Diabetic dermopathy (14.8%), acanthosis nigricans (4.9%), and Diabetic thick skin seen in 4% etc. The overall prevalence of cutaneous lesions in this study was 73%.
Journal of Diabetes & Metabolism, 2018
Introduction: Diabetes leads to destruction all over the body and the skin is not exempted from the attack. The skin shares both the effects of acute gross metabolic derangement and chronic degenerative changes of diabetes, as it are an actively metabolizing tissue. Aims and objectives: To study the clinical patterns of dermatological manifestations of diabetes mellitus in the region of eastern India. Methods: Sixty consecutive subjects with diabetes mellitus having dermatological manifestations and satisfying the inclusion criteria were included in this study. Results: Bacterial infections were the commonest dermatological disorder (46.7%). Different forms of dermatophyte infections and candidiasis were found in 30% and 23.3% subjects, respectively. Diabetic dermopathy or 'shin spot' and diabetic foot with gangrenous changes were found in 20% and 13.3% subjects, respectively. Skin manifestations associated with diabetes were the second most common skin disorders and constituted 43.3% (26 out of 60 cases). Pruritus of unknown origin and xerosis (13.3%) were the most common cutaneous abnormalities in the group associated with diabetes. Other cutaneous manifestations, namely pigmented purpuric dermatosis (6.6%), psoriasis (3.3%), vitiligo (6.6%), lichen planus (3.3%), porokeartosis (3.3%), sclerosis, diabetic thick skin and contracture (6.6%), lipodystrophy (3.3%), skin rashes (6.6%) and scar with abscess (1.6%), were very rare. Conclusions: Our study has provided some insights into the pattern of dermatological manifestations in diabetes mellitus. A larger prospective study will further consolidate our main objective that management of diabetes is a holistic one and due attention on skin complications is warranted.
Skin lesions in diabetes mellitus: prevalence and clinical correlations
Diabetes Research and Clinical Practice, 1998
With the aim to assess the prevalence and the main clinical correlations of skin lesions in diabetes mellitus, 457 diabetic subjects consecutively attending an outpatient clinic underwent a dermatological examination. Neurovascular foot lesions were excluded. Thirty-five of 64 IDDM patients (54%) had skin alterations mainly consisting of vitiligo (9% of all patients), psoriasis (9%) and eczema (8%). The most frequent skin lesions observed in 240/393 NIDDM subjects (61%) were represented by infections (20% of all patients) and diabetic dermopathy (12.5%), while other lesions were not common. NIDDM patients with skin infections had a worse metabolic control, and those with diabetic dermopathy had a greater prevalence of neuropathy and large vessel disease than patients without skin lesions. These data show that the prevalence of skin diseases in a large, unselected diabetic population is higher than expected and indicate that, in most cases, a careful dermatological examination and a better metabolic control are needed in order to improve quality of life in these patients.
The Open Dermatology Journal Recent Insights On Diabetic Dermopathy
Background: Diabetic dermopathy consists of small, round, brown atrophic skin lesions that occur on the shins of patients with diabetes. Its proper diagnosis is essential for proper management. Objective: The present study has been undertaken to study the complications, signs, symptoms, prevention and cure of dermopathy caused by diabetes. Material and Methods: Dermopathy was studied in brief with the help of literature available in the form of articles, various databases, medical news, etc. Result: Proper diagnosis and cure are necessary at early stages to prevent future complications associated with it. Conclusion: Diabetic dermopathy requires no treatment, but may be a surrogate for more serious complications of diabetes, which require investigation and management.
Skin disorders in diabetes mellitus: an epidemiology and physiopathology review
Diabetology & Metabolic Syndrome, 2016
Skin disorders, usually neglected and frequently underdiagnosed among diabetic patients, are common complications and encounter a broad spectrum of disorders in both type 1 and type 2 diabetes mellitus (DM)-e.g. cutaneous infection, dry skin, pruritus. Skin disorders are highly associated with increased risk of important outcomes, such as skin lesions, ulcerations and diabetic foot, which can lead to major complications and revolve around multifactorial factors besides hyperglycemia and advanced glycation end products. Although diabetic's skin disorders are consistent in the literature, there is limited data regarding early-stage skin disorders in DM patients. Disease control, early-stage treatment (e.g. skin hydration, orthotic devices) and awareness can reduce morbidity of DM patients. Thus, better understanding of the burden of skin disorders in DM patients may raise awareness on prevention and management. Therefore, the aim of this study is to perform a literature review to evaluate the main clinical characteristics and complications of skin disorders in diabetic's patients. Additionally, physiopathology early-stage skin disorders and dermocosmetic management were also reviewed.
Diabetes mellitus and the skin
The Practitioner, 1969
Several dermatoses are routinely associated with diabetes mellitus, especially in patients with chronic disease. This relationship can be easily proven in some skin disorders, but it is not so clear in others. Dermatoses such necrobiosis lipoidica, granuloma annulare, acanthosis nigricans and others are discussed in this text, with an emphasis on proven link with the diabetes or not, disease identification and treatment strategy used to control those dermatoses and diabetes.
The prevalence of skin disorders in type-2 diabetic patients
Int J Dermatol, 2005
Objective: Little information is available about the prevalence of skin disorders among type-2 diabetic patients. The aim of our study was to evaluate the frequency of dermatologic disorders in patients with type-2 diabetes mellitus.
Dermatological Manifestations in Diabetes Mellitus at NGMCTH Kohalpur
Journal of Nepalgunj Medical College, 2017
Background: Skin is the largest and most visible organ in the body. It undoubtedly determines to a great extent our appearance and plays a major role in socio-sexual communication. More than one third of diabetic patients have some type of dermatologic 1 manifestations during the course of their chronic disease. The association of certain skin diseases with diabetes mellitus has been 2 3 fairly well recognized with an incidence rate ranging from 11.4% to 66%. At least 30% of patients with diabetes mellitus have some 4 5 type of cutaneous involvement during the course of their chronic disease. Skin sugar levels run parallel to the blood sugar levels. Skin changes generally appear subsequent to the development of DM but may be the first presenting sign or even precede the 6 diagnosis by many years. Among the many skin manifestations in DM, none is pathognomonic of this disease. Cutaneous findings in DM can be classified into four categories: (1) skin disease with strong association and others with less distinct association with DM, (2) cutaneous infections, (3) dermatological disorders related to diabetic complications, and (4) skin conditions related to diabetes 7 treatment. Objectives: This study was undertaken to find out the pattern of Dermatological manifestations in Diabetes patients
Pattern of cutaneous manifestations in diabetes mellitus
Indian Journal of Dermatology, 2010
Background: Diabetes mellitus affects individuals of all ages and socioeconomic status. Skin is affected by the acute metabolic derangements as well as by chronic degenerative complications of diabetes. Aims: To evaluate the prevalence of skin manifestations in patients with diabetes mellitus. To analyze the prevalence and pattern of skin disorders among diabetic patients from this region of Western Himalayas. Materials and Methods: One hundred consecutive patients with the diagnosis of diabetes mellitus and having skin lesions, either attending the diabetic clinic or admitted in medical wards were included in this study. Results: The common skin disorders were: Xerosis (44%), diabetic dermopathy (36%), skin tags (32%), cutaneous infections (31%), and seborrheic keratosis (30%). Conclusion: Skin is involved in diabetes quite often and the manifestations are numerous. High prevalence of xerosis in our diabetic population is perhaps due to cold and dry climatic conditions in the region for most of the time in the year.
A study on the cutaneous manifestations of diabetes mellitus
diabetic foot
The cutaneous manifestations of diabetes mellitus are varied. We conducted a study of fifty patients having diabetes mellitus coming from the department of dermatology and medicine. The commonest cutaneous feature of diabetes were pyodermas seen in 40% patients, dermatophytosis seen in 36% patients, pruritis diabetic thick skin seen in 20 % patients, diabetic dermopathy seen in 16% patients, diabetic bulla and rubeosis seen in 8% patients each and meralgia paraesthetica and diabetic foot seen in 4% patients each. About the associations of diabetes mellitus, achrchordons were seen in 8% patients, vitiligo and perforating dermatoses were seen in 6% patients each, granuloma annulare, eruptive xanthomas, acanthosis nigricans, necrobiosis lipoidica and oral lichen planus were seen in 4 % patients each and xanthelasma was seen in 2% patients.