Non–Small Cell Lung Cancer: Histopathologic Correlates for Texture Parameters at CT (original) (raw)

Standard deviation (SD) of the histogram and mean value of the positive pixels (MPP) quantified from medium texture scale (1.8 to 3.0 mm in width) to coarse texture scale (3.6 mm in width) on CE-CT showed significant associations with tumor staining by Pimonidazole (coarse texture, SD, slope=0.003, p=0.0003). 2. Uniformity of the distribution of the positive pixels (UPP) for image features (medium to coarse texture) on non-CE CT showed a significant inverse association with tumor GLUT-1 expression (coarse texture, slope=-115.13, p=0.0008). 3. MPP quantified from medium to coarse texture on both non-CE and CE-CT showed significant inverse associations with tumor CD34 expression (non-CE CT: medium texture, slope=-0.0008, p=0.003 and CE-CT: medium texture, slope=-0.0006, p=0.004).