Aneuploidy and Epithelial Cancers: The Impact of Aneuploidy on the Genesis, Progression and Prognosis of Colorectal and Breast Carcinomas (original) (raw)

2012, Aneuploidy in Health and Disease

AI-generated Abstract

Aneuploidy is a hallmark of epithelial cancers such as colorectal and breast carcinoma, significantly influencing their genesis, progression, and prognosis. The existence of genomic imbalances correlates with worse clinical outcomes, independent of tumor stage, and highlights aneuploidy as a critical prognostic factor. This research underscores the need to better understand aneuploidy’s role in cancer pathogenesis and its potential utility in diagnostics and therapeutic strategies.

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