Hedgehog-Gli Signaling Pathway Inhibitors as Anticancer Agents (original) (raw)

The role of the Hedgehog signaling pathway in cancer A comprehensive review

BJBMS Journal

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Clinical implications of hedgehog signaling pathway inhibitors

Dongsheng Gu

Chinese Journal of Cancer, 2011

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Review: Targeting the Hedgehog pathway in cancer

Naoko Takebe

Therapeutic Advances in Medical Oncology, 2010

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Hedgehog signalling pathway: Carcinogenesis and targeted therapy

Mohamad Ebrahimi

Iranian Journal of Cancer Prevention, 2013

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Targeting GLI factors to inhibit the Hedgehog pathway

Lucia Di Marcotullio

Trends in Pharmacological Sciences, 2015

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Small-Molecule Inhibitors of the Hedgehog Signaling Pathway as Cancer Therapeutics

Stefan Peukert

ChemMedChem, 2010

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Intricacies of hedgehog signaling pathways: A perspective in tumorigenesis

Swayamsiddha Kar

Experimental Cell Research, 2012

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The Hedgehog Signaling Pathway: A Promising Target for Therapeutic Development

Nahla Hamed

Cancer therapy & Oncology International Journal

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Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade

Paul Rack

Proceedings of the National Academy of Sciences, 2009

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Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells

Andrea Loipetzberger

EMBO Molecular Medicine, 2012

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Hedgehog Signaling: An emerging targeting therapy in Cancer

Urja Desai

Asian Journal of Pharmacy and Pharmacology

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Hedgehog signaling pathway and its targets for treatment in basal cell carcinoma

Enrico Smaele

Journal of Experimental Pharmacology, 2012

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Targeting Hedgehog signaling and understanding refractory response to treatment with Hedgehog pathway inhibitors

Maikel Peppelenbosch

Drug Resistance Updates, 2012

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Structural and Logical Analysis of a Comprehensive Hedgehog Signaling Pathway to Identify Alternative Drug Targets for Glioma, Colon and Pancreatic Cancer

SAIKAT CHOWDHURY

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A paracrine requirement for hedgehog signalling in cancer

Tracy Tang

Nature, 2008

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Identification of a small molecule inhibitor of the hedgehog signaling pathway: Effects on basal cell carcinoma-like lesions

Lee Ling Chai

Proceedings of The National Academy of Sciences, 2003

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GDC-0449—A potent inhibitor of the hedgehog pathway

Janet Gunzner

Bioorganic & Medicinal Chemistry Letters, 2009

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Hedgehog Signaling in Development and Cancer

Chi-chung Hui

Developmental Cell, 2008

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Signalling Pathways Driving Cancer Stem Cells: Hedgehog Pathway

Luis Ernesto ( L U I S ) Barrionuevo Aparicio

Cancer Stem Cells Theories and Practice, 2011

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Frequent Deregulations in the Hedgehog Signaling Network and Cross-Talks with the Epidermal Growth Factor Receptor Pathway Involved in Cancer Progression and Targeted Therapies

Murielle Mimeault

Pharmacological Reviews, 2010

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In vitro and in vivo characterization of a novel hedgehog signaling antagonist in human glioblastoma cell lines

Patrizia Tunici

International Journal of Cancer, 2012

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MK-4101, a Potent Inhibitor of the Hedgehog Pathway, Is Highly Active against Medulloblastoma and Basal Cell Carcinoma

Gessica Filocamo

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Aberrant Activation of the Hedgehog Signaling Pathway in Malignant Hematological Neoplasms

Rajesh R Singh

The American Journal of Pathology, 2012

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Hedgehog signaling pathway is inactive in colorectal cancer cell lines

Naima Boussif

International Journal of Cancer, 2007

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The Role of Smoothened-Dependent and -Independent Hedgehog Signaling Pathway in Tumorigenesis

Vaisnevee Sugumar

Biomedicines

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A Smo/Gli Multitarget Hedgehog Pathway Inhibitor Impairs Tumor Growth

Lucia Di Marcotullio

Cancers

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