Probing the Agonist Domain of the Nicotinic Acetylcholine Receptor by Cysteine Scanning Mutagenesis Reveals Residues in Proximity to the α-Bungarotoxin Binding Site † (original) (raw)

Biochemistry, 1991

Identification of Equivalent Residues in the gamma , delta , and epsilon Subunits of the Nicotinic Receptor That Contribute to alpha -Bungarotoxin Binding

Steven m. M Sine

Journal of Biological Chemistry, 1997

Biotinylation of Substituted Cysteines in the Nicotinic Acetylcholine Receptor Reveals Distinct Binding Modes for alpha -Bungarotoxin and Erabutoxin a

Journal of Biological Chemistry, 2000

Chimeric Analysis of a Neuronal Nicotinic Acetylcholine Receptor Reveals Amino Acids Conferring Sensitivity to α-Bungarotoxin

Journal of Biological Chemistry, 1999

An .alpha.-Bungarotoxin-Binding Sequence on the Torpedo Nicotinic Acetylcholine Receptor .alpha.-Subunit: Conservative Amino Acid Substitutions Reveal Side-Chain Specific Interactions

Biochemistry, 1994

Structural determinants within residues 180-199 of the rodent .alpha.5 nicotinic acetylcholine receptor subunit involved in .alpha.-bungarotoxin binding

Biochemistry, 1991

The α-bungarotoxin binding site on the nicotinic acetylcholine receptor: Analysis using a phageepitope library

Moshe Balass

Proceedings of the …, 1997

NMR Structure of α-Bungarotoxin Free and Bound to a Mimotope of the Nicotinic Acetylcholine Receptor †

Ottavia Spiga

Biochemistry, 2002

Rearrangement of Nicotinic Receptor α Subunits during Formation of the Ligand Binding Sites

The Journal of Neuroscience, 2001

The ligand binding domain of the nicotinic acetylcholine receptor

Sylvia Kachalsky

FEBS Letters, 1993

NMR structure of alpha-bungarotoxin free and bound to a mimotope of the nicotinic acetylcholine receptor

Ottavia Spiga

Biochemistry, 2002

Nonequivalence of .alpha.-bungarotoxin binding sites in the native nicotinic receptor molecule

Warren Gallagher

Biochemistry, 1990

The binding site of the acetylcholine receptor: Correlation between structure and α-bungarotoxin binding

Sylvia Kachalsky

Neuromuscular Disorders, 1994

The binding site for α-bungarotoxin resides in the sequence 188–201 of the α-subunit of acetylcholine receptor: Structure, conformation and binding characteristics of peptide [Lys] 188–201

FRANCESCO CLEMENTI

Neuroscience Letters, 1987

Neuronal α-Bungarotoxin Receptors Differ Structurally from Other Nicotinic Acetylcholine Receptors

The Journal of Neuroscience, 1997

Histidine 186 of the nicotinic acetylcholine receptor α subunit requires the presence of the 192–193 disulfide bridge to interact with α-bungarotoxin

Fernando Testai

Neurochemistry International, 2000

An H-bond between two residues from different loops of the acetylcholine binding site contributes to the activation mechanism of nicotinic receptors

Stuart Edelstein

The EMBO Journal, 2003

Covalent modification of engineered cysteines in the nicotinic acetylcholine receptor agonist-binding domain inhibits receptor activation

Biochemical Journal, 1995

Identification of regions involved in the binding of α-bungarotoxin to the human α7 neuronal nicotinic acetylcholine receptor using synthetic peptides

Martha Marinou

Biochemical Journal, 2003

Formation of the α-Bungarotoxin Binding Site and Assembly of the Nicotinic Acetylcholine Receptor Subunits Occur in the Endoplasmic Reticulum

McHardy Smith

Purification and characterization of an alpha-bungarotoxin receptor that forms a functional nicotinic channel

cecilia Gotti

Proceedings of the National Academy of Sciences of the United States of America, 1991

Preliminary Two-Dimensional [1H]NMR Characterization of the Complex Formed between an 18-Amino Acid Peptide Fragment of the α-Subunit of the Nicotinic Acetylcholine Receptor and α-Bungarotoxina

Annals of the New York Academy of Sciences, 1995

Yeast Expression and NMR Analysis of the Extracellular Domain of Muscle Nicotinic Acetylcholine Receptor alpha Subunit

Jordan Chill

Journal of Biological Chemistry, 2002

Emerging structure of the Nicotinic Acetylcholine receptors

Arthur KARLIN

Nature Reviews Neuroscience, 2002

Molecular basis of the two nonequivalent ligand binding sites of the muscle nicotinic acetylcholine receptor

P. Blount

Neuron, 1989

Formation of the Nicotinic Acetylcholine Receptor Binding Sites

The Journal of Neuroscience, 1998

Amino Acid Residues That Confer High Selectivity of the 6 Nicotinic Acetylcholine Receptor Subunit to -Conotoxin MII[S4A,E11A,L15A]

Layla Azam

Journal of Biological Chemistry, 2008

Counting Bungarotoxin Binding Sites of Nicotinic Acetylcholine Receptors in Mammalian Cells with High Signal/Noise Ratios

Biophysical Journal, 2010

Docking of α-cobratoxin suggests a basal conformation of the nicotinic receptor

Maria Konstantakaki

Biochemical and Biophysical Research Communications, 2007

Localization of sequence segments forming a kappa-bungarotoxin-binding site on the alpha 3 neuronal nicotinic receptor

Journal of Biological Chemistry, 1990

Docking of alpha-cobratoxin suggests a basal conformation of the nicotinic receptor

Maria Konstantakaki

Biochemical and biophysical research communications, 2007

Negatively charged amino acid residues in the nicotinic receptor delta subunit that contribute to the binding of acetylcholine

Arthur KARLIN

Proceedings of the National Academy of Sciences, 1993

Engineering neuronal nicotinic acetylcholine receptors with functional sensitivity to Î±-bungarotoxin: a novel Î±3-knock-in mouse

tanya sanders

European Journal of Neuroscience, 2009

Rearrangement of Nicotinic Receptor a Subunits during Formation of the Ligand Binding Sites

2001

Inter-residue coupling contributes to high-affinity subtype-selective binding of α-bungarotoxin to nicotinic receptors

Steven m. M Sine

Biochemical Journal, 2013