Factors Influencing Adherence to Tuberculosis Treatment in the Ketu North District of the Volta Region, Ghana (original) (raw)

Tuberculosis treatment adherence in Ghana: patients’ perspectives of barriers and enablers to treatment

2017

Tuberculosis (TB) treatment continues to be a daunting task in most low and middle- income countries due to cultural beliefs held by people and inadequate information about the importance of treatment adherence in the community. This study explored the patient-related factors influencing tuberculosis treatment adherence, with a focus on patient-related factors affecting such treatment adherence. Using a semi-structured interview guide, 10 participants (Five males, five females) were engaged in in-depth individual interviews. Miles and Huberman’s (1994) content analysis approach was used to analyse data. Three main themes emerged from the synthesised data: Knowledge on TB and its treatment, challenges associated with TB treatment and motivating factors to adherence. Patients’ belief about the cause of TB such as spiritual forces, poor knowledge about treatment duration and consequences of defaulting, and the side effect of drugs especially when taken with little or no food were found...

Patients’ Compliance with Tuberculosis Medication in Ghana: Evidence from a Periurban Community

Advances in Public Health, 2015

Globally, an estimated 2 million deaths occur every year as a result of tuberculosis. Ghana records over 46,000 new cases annually despite numerous efforts to curb the disease. One major challenge associated with the control of the disease is patients’ noncompliance with medication. Despite the noncompliance setback, not much information is available on the issue. This paper, therefore, examines patients’ compliance with medication at the Suhum Kraboa Coaltar District in Ghana. A cross-sectional descriptive study was carried out using interview schedules. Data were primarily retrieved from 40 treatment supporters, in addition to 110 previously treated persons registered in 2010 and 2011 with cases of pulmonary tuberculosis. Evidence from the study indicates that 63 percent of the previously treated persons complied with medication which is below the expected national target of at least 85 percent. However, those with treatment supporters significantly complied with medication. Depre...

Assessment of Factors Contributing to TB Treatment Adherence among Patients on TB Treatment in Kano State, Nigeria: A Case Study

Journal of Tuberculosis Research, 2020

Background: The WHO recommended DOTS has been proven to be very effective in the treatment of tuberculosis (TB) patients. However, despite its effectiveness, non-adherence to the treatment regimen remains a major concern in TB management. This has great consequences which include persistent infectiousness, higher rates of treatment failure, continued transmission, drug resistance, and untimely death. The aim of this study is to examine the factors and behavioural patterns that contribute to treatment adherence among TB patients in Kano State, Nigeria. Methods: A qualitative study design which included two focus group discussions (FGDs) and four key informant interviews (KIIs) were adopted for this study. In total, 20 participants were interviewed comprising 16 focus group discussion participants (8 patients on treatment and 8 individuals who have been cured) divided into two groups and four key informant interviews with 4 health workers in the selected treatment facilities. Data analysis was done by translating and transcribing the responses from the FGDs and KIIs. The transcribed data was analysed using a thematic framework procedure. Results: It was observed that having a good treatment supporter who was effective and very supportive was the most important factor contributing to treatment adherence. Other identified factors that contributed to treatment adherence included: good communication by health personnel, social support from relatives and communities, little or no side effects from drug usage, low cost of transportation to the health facilities, a positive mind set towards drug usage and treatment, support and motivation from health workers, feelings of wellness during treatment, and a balanced diet. All the respondents agreed that treatment adherence had far reaching effects on positive treatment outcomes. Conclusion:

Health service factors that affect adherence to tuberculosis treatment in Ghana

Primary Health Care, 2018

Almost ninety percent of the global tuberculosis is found in Asia, Africa, and other continents. This is largely due to deficient educational information, myths, beliefs, and suboptimal service delivery as a result of inadequate infrastructure. Even though proper treatment of TB can cure the disease, the bureaucratic difficulties and customer care issues have raised concerns that the procedures put in place to ensure that patients with TB receive and complete treatment now stifle the treatment regime. This paper looked at the servicedelivery factors that affect TB treatment adherence while seeking to explore good practices to develop improving support for the care of TB patients. The study adopted a qualitative interpretive descriptive design using interviews, across health facilities in one district in Ashanti Region, Ghana. Ten participants made up of (5 men; 5 women; median age 36) were recruited in 2014 and interviewed. Patients revealed varying degrees of challenges and facilitators that affected their adherence to TB treatment. Three 2 main themes were identified: good institutional support, unpleasant patient-staff encounters, and unmet care needs. Staff commitment, proper supervision of TB patients and individualising care encourages adherence while organisational challenges, poor supervision of patients and unfriendly staff attitude discourage the continuity of treatment.

Adherence to Tuberculosis Therapy in Unilorin Teaching Hospital, Ilorin, North-Central Nigeria

2013

Introduction: Non-adherence to treatment has been one of the main obstacles to the control of tuberculosis. The objective of this study is to investigate the rate of adherence to medication among Tuberculosis (TB) patients. Methodology: This study was a descriptive, cross-sectional survey with analysis of the observed variables in tuberculosis patients. All adults aged 18years and above who were accessing treatment for tuberculosis at the chest clinic of the University of Ilorin Teaching Hospital, Kwara Statewere recruited for the study until the desired sample size of 544 was obtained. The sample size was determined using Fisher’s Formula. Structured, pre-tested interviewer – administered questionnaire was used for data collection and data were analyzed using SPSS version 16. Frequency tables and cross-tabulation of variables were done and pvalue <0.05 was used to determine statistical significance. Result: Respondents who had taken Anti-Tuberculosis drugs for 3-6 months [mean d...

Factors Influencing Non Adherence to Directly Observed Treatment Short Course among Patients with Tuberculosis in Selected Secondary Health Facilities, Ibadan, Oyo State, Nigeria

Tuberculosis is a global threat that contributes to disease burden especially in developing countries including Nigeria. Effect of non adherence to directly observed treatments short course (DOTS) leads to continuous infectivity, development of drug resistance and increased mortality associated with Tuberculosis (TB). Therefore, the objective of this study is to identify factors influencing non adherence to directly observed treatments short course among patients with tuberculosis. The study utilized descriptive research design survey. The sample consisted of 163 patients with Tuberculosis using simple random sampling technique. A selfdeveloped structured questionnaire with reliability index of 0.832 was used to collect data. Data collected were coded and analysed using SPSS version 25. Descriptive statistics of frequencies, percentages were used to answer the research questions while the stated hypotheses were analysed using regression. The results from the study revealed high level of non-adherence to DOTS, low level of knowledge on TB treatment. The results further revealed a significant relationship between socio-demographic factors, knowledge of TB treatment and non-adherence to TB medications at 0.05 level of significance. Therefore, the study established a very high level of non-adherence of TB patients to DOTS which is associated with sociodemographic factors and level of knowledge on TB treatments. It is recommended that the stakeholders in the management of TB patient should ensure frequent health educations, increase the numbers of health worker, reduce the duration of time spent in the hospital, improve follow up strategies, and other policies that can lead to improve adherence of TB patients to DOTs

Level of Adherence To Tuberculosis Therapy In Adult Tuberculosis Patients At Chilenje Clinic In Lusaka

2016

Chilenje clinic in Lusaka. METHOD; A cross section study was used. The study site wasChilenje clinic in Lusaka and the target population were all TB patients who were on TB therapy between the period from January 2013 to July 2015.The study sample of 321 TB patient's files was selected using a simple random technique on excel version 13. Data collected from patient's files was entered on the data sheet and SPSS version16 .0 for analysis. DATA ANALYSIS; A descriptive analysis was carried out according to the characteristics of variables. Since the study was capturing nominal and categorical variables such as treatment defaulters, missed appointments, therapy completion etc. the percentages were obtained and cross tabulations were done to determine the Pearsons value and the graphical presentations such as the pie charts and bar charts were designed in excel version 13. RESULTS: the study found that 69% of patients completed TB treatment, 15defaulted and 16% died during therapy. The study did not find any significant association between patient's age group, sex and category of treatment with patient adherence to TB treatment. The study however found a significant association between the patient's HIV status and adherence to TB treatment.

Level of and associated factors for non-adherence to anti-tuberculosis treatment among tuberculosis patients in Gamo Gofa zone, southern Ethiopia: cross-sectional study

BMC Public Health, 2020

Background: Non-adherence to anti-TB treatment is one of the crucial challenges in improving tuberculosis (TB) treatment outcomes and reducing healthcare costs. The poor adherence to anti-TB treatment among patients with TB is a major problem in Ethiopia. This study aimed to assess the level of and associated factors for non-adherence to anti-TB therapy among patients with tuberculosis in the Gamo Gofa Zone. Methods: A cross-sectional study was conducted at Gamo Gofa Zone from July 20-August 30, 2017. A multistage sampling technique was used. The study included 289 patients who were on anti-TB treatment. Data were collected by trained data collectors using a structured and pre-tested questionnaire through interviews. A multiple logistic regression model was fitted using SPSS 23 to identify factors associated with non-adherence to anti-TB treatment at a 5% significance level. Results: We found that 16.5% of the participants were non-adherent for anti-TB treatment. Failure to disclose one's TB status to his or her family (AOR = 31.7; 95% CI: 9.1-111.1), having no information on the expected adverse events (AOR = 31.1; 95% CI: 7.5-128.3), past anti-TB treatment history (AOR = 5.3; 95% CI: 1.5-18.8) and a smoking cigarette (AOR = 11.7; 95% CI: 3.2-43.03) were found to be associated with a higher odds of being non-adherent to anti-TB treatment. Conclusions: The level of non-adherence to anti-TB treatment among TB patients was high. Health care providers should counsel TB patients on the expected adverse events and measures to be taken when patients face the expected adverse events. They should also counsel their patients to disclose their TB status to his or her family and for ceasing cigarette smoking.

Barriers to tuberculosis treatment adherence in high-burden tuberculosis settings in Ashanti region, Ghana: a qualitative study from patient’s perspective

BMC Public Health

Background Despite having an effective community-based Directly Observed Therapy Short-course (DOTS) strategy for tuberculosis (TB) care, treatment adherence has been a major challenge in many developing countries including Ghana. Poor adherence results in discontinuity of treatment and leads to adverse treatment outcomes which pose an increased risk of drug resistance. This study explored barriers to TB treatment adherence and recommended potential patient-centered strategies to improve treatment adherence in two high-burden TB settings in the Ashanti region of Ghana. Methods The study was conducted among TB patients who defaulted on treatment in the Obuasi Municipal and Obuasi East districts in the Ashanti region. A qualitative phenomenology approach was used to explore the barriers to TB treatment adherence. Purposive sampling was adopted to select study participants with different sociodemographic backgrounds and experiences with TB care. Eligible participants were selected by r...

Adherence to Tuberculosis in Unilorin Teaching Hospital, Ilorin, North Central Nigeria

Abstract: Introduction: Non-adherence to treatment has been one of the main obstacles to the control of tuberculosis. The objective of this study is to investigate the rate of adherence to medication among Tuberculosis (TB) patients. Methodology: This study was a descriptive, cross-sectional survey with analysis of the observed variables in tuberculosis patients. All adults aged 18years and above who were accessing treatment for tuberculosis at the chest clinic of the University of Ilorin Teaching Hospital, Kwara Statewere recruited for the study until the desired sample size of 544 was obtained. The sample size was determined using Fisher’s Formula. Structured, pre-tested interviewer – administered questionnaire was used for data collection and data were analyzed using SPSS version 16. Frequency tables and cross-tabulation of variables were done and p- value <0.05 was used to determine statistical significance. Result: Respondents who had taken Anti-Tuberculosis drugs for 3-6 mo...